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WRONG ! Cholesterol is a red herring.</p>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/cholesterol/gallstones-cholesterol-problem/\">Gallstones are NOT a cholesterol problem</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:32:\"http://purl.org/dc/elements/1.1/\";a:1:{s:7:\"creator\";a:1:{i:0;a:5:{s:4:\"data\";s:8:\"Dr Sandy\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:40:\"http://purl.org/rss/1.0/modules/content/\";a:1:{s:7:\"encoded\";a:1:{i:0;a:5:{s:4:\"data\";s:14526:\"<p><iframe src=\"https://www.youtube.com/embed/PvJuaBx0qR0\" width=\"640\" height=\"480\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"></iframe></p>\n\n<p>Click to listen to the audio…<br />\n<script type=\"text/javascript\" src=\"//spoonfulofscience.audello.com/player/Y2hvbGVzdGVyb2wtbWlnaHQtYmUtaW4tZ2FsbHN0b25lcy1idXQtaXQtaXMtbm90LXQubXAz/?container=audello-E2T5R7BMYX\" async></script></p>\n<div id=\"audello-E2T5R7BMYX\" class=\"audello-player audello-file\" data-role=\"audello-file\" data-audello-id=\"Y2hvbGVzdGVyb2wtbWlnaHQtYmUtaW4tZ2FsbHN0b25lcy1idXQtaXQtaXMtbm90LXQubXAz\"></div>\n<h1 style=\"text-align: center;\">Gallstones are NOT a cholesterol problem</h1>\n<div id=\"attachment_19267\" style=\"width: 410px\" class=\"wp-caption alignright\"><img class=\"size-full wp-image-19267\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/gallbladder-crying-no-bile-acid-flowers.png\" alt=\"gallbladder crying\" width=\"400\" height=\"595\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/gallbladder-crying-no-bile-acid-flowers.png 400w, https://betterbodychemistry.com/wp-content/uploads/2019/03/gallbladder-crying-no-bile-acid-flowers-202x300.png 202w\" sizes=\"(max-width: 400px) 100vw, 400px\" /><p class=\"wp-caption-text\">Since gallstones are made of cholesterol, logic says, to prevent gallstone disease, cholesterol levels should be as low as possible. WRONG ! Cholesterol is a red herring.</p></div>\n<p>Most gallstones are made of cholesterol….</p>\n<p>So, putting two and two together, if you want to “makeâ€� a gallstone, you need “lots of cholesterolâ€�.</p>\n<p>And this is precisely what happens….</p>\n<h2><span style=\"color: #f21f02;\"><strong>Bile supersaturated with cholesterol</strong></span></h2>\n<p>When bile is collected and analysed, someone with gallstone disease, will have bile that is supersaturated with cholesterol.  Doctors quantify this, using the cholesterol saturation index or CSI for short.</p>\n<p>So if your CSI is high………..</p>\n<h3 style=\"text-align: center;\">BE WARNED, you ARE at risk of a gallstone.</h3>\n<h2><span style=\"color: #f21f02;\"><strong>Stop that “highâ€� cholesterol</strong></span></h2>\n<p>Since you MUST BE secreting, TOO MUCH cholesterol, into the bile, to mitigate your risk, you must do what you can to lower cholesterol levels.</p>\n<h2 style=\"text-align: center;\">Don’t eat it. Don’t make it. Excrete it.</h2>\n<p>Well that is the current thinking……but it’s “wrongâ€� !</p>\n<p>This is what a team of researchers from the Karolinska Institute discovered, when they changed the way, the cholesterol levels, in the bile, were reported.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Bile is a mixture</strong></span></h2>\n<p>The three big ingredients are</p>\n<ul>\n<li>Cholesterol</li>\n<li>Bile acids</li>\n<li>Phospholipids</li>\n</ul>\n<p>When the CSI is calculated, the three ingredients are expressed as a percentage (mol % value) of each other.</p>\n<p><img class=\"aligncenter size-full wp-image-19268\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/CSI-equation.png\" alt=\"Cholesterol saturation index equation\" width=\"682\" height=\"360\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/CSI-equation.png 682w, https://betterbodychemistry.com/wp-content/uploads/2019/03/CSI-equation-300x158.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/03/CSI-equation-300x158@2x.png 600w\" sizes=\"(max-width: 682px) 100vw, 682px\" /></p>\n<h2><strong>The cholesterol percentage</strong></h2>\n<p>So  “normalâ€� bile, would typically have….</p>\n<p style=\"text-align: center;\">Cholesterol levels around 5 %.</p>\n<p>And when someone has lithogenic bile i.e. bile that favors gallstone formation, the amount of cholesterol is definitely up, typically……….</p>\n<h3 style=\"text-align: center;\">The cholesterol levels DOUBLE, to around 10 %.</h3>\n<p>Of course, since the calculation is based on total number of molecules, if there are more cholesterol molecules, there must be less bile acid and/or phospholipid molecules, present.</p>\n<p>But that does not mean there is actually more cholesterol………</p>\n<h2><span style=\"color: #f21f02;\"><strong>The concentration of cholesterol</strong></span></h2>\n<p>To get the full picture, we need to know exactly how much cholesterol  there is.</p>\n<p style=\"text-align: center;\">So this is what our team did.</p>\n<p>Using historical data, from 232 gall bladder removal surgeries, which took place between 1981 and 1998, the team, calculated the actual amount of cholesterol, in the bile samples.</p>\n<p><em>NOTE : There were 145 patients with cholesterol gallstones (111 women, 34 men) and 87 without gallstones (73 women, 14 males). </em></p>\n<h2><em> </em><span style=\"color: #f21f02;\"><strong>Cholesterol levels unchanged</strong></span></h2>\n<p>When they did this calculation, they found, the cholesterol levels in the bile of  people with gallstones, was not higher.</p>\n<p><img class=\"aligncenter size-full wp-image-19269\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/cholesterol-concentration-in-bile-samples.png\" alt=\"cholesterol concentrations in bile\" width=\"530\" height=\"302\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/cholesterol-concentration-in-bile-samples.png 530w, https://betterbodychemistry.com/wp-content/uploads/2019/03/cholesterol-concentration-in-bile-samples-300x171.png 300w\" sizes=\"(max-width: 530px) 100vw, 530px\" /></p>\n<h3 style=\"text-align: center;\">In fact,cholesterol levels, were exactly the same.</h3>\n<p>Accordingly, the idea, that their liver was pumping excess cholesterol into their gallbladder, causing the problem, was not correct.</p>\n<p>So what was the problem ?</p>\n<h2><span style=\"color: #f21f02;\"><strong>Bile acids were missing</strong></span></h2>\n<p>When they measured the absolute levels, the thing that stood out, was the bile acids were “missingâ€�, i.e.</p>\n<h2 style=\"text-align: center;\">People with gallstones had a bile acid deficiency</h2>\n<p><img class=\"aligncenter size-full wp-image-19270\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/bile-acids-in-bile-samples.png\" alt=\"bile acid levels in bile samples\" width=\"553\" height=\"302\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/bile-acids-in-bile-samples.png 553w, https://betterbodychemistry.com/wp-content/uploads/2019/03/bile-acids-in-bile-samples-300x164.png 300w\" sizes=\"(max-width: 553px) 100vw, 553px\" /></p>\n<h2 style=\"text-align: center;\">NOT a cholesterol excess.</h2>\n<p>Really ?  The team decided to probe other sets of published data, to see if the pattern persisted.</p>\n<p>It did……</p>\n<p>Here is a table, summarizing their findings. When there is a red box, the value is increased, when there is a blue box, the value is decreased. All but one of the 13 studies analysed, showed bile acids were  significantly lower.</p>\n<div id=\"attachment_19271\" style=\"width: 556px\" class=\"wp-caption aligncenter\"><img class=\"size-full wp-image-19271\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/cholesterol-versus-cholesterol-concentration-in-bile-samples.png\" alt=\"Gallstone lipid levels\" width=\"546\" height=\"333\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/cholesterol-versus-cholesterol-concentration-in-bile-samples.png 546w, https://betterbodychemistry.com/wp-content/uploads/2019/03/cholesterol-versus-cholesterol-concentration-in-bile-samples-300x183.png 300w\" sizes=\"(max-width: 546px) 100vw, 546px\" /><p class=\"wp-caption-text\">Comparison of the differences between gallbladder lipids from bile samples with / without gallstones. Expressed as % mol versus concentration. Copyright © 2019 Rudling et al.</p></div>\n<h2><span style=\"color: #f21f02;\"><strong>Too much cholesterol is a red herring</strong></span></h2>\n<p>The real problem, in gallstone disease, is a bile acid deficiency !</p>\n<p>So the plan of attack, if you want to mitigate the risk of a gallstone,  needs to shift from cholesterol lowering, to correcting the bile acid deficiency.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Where have the bile acids gone ? </strong></span></h2>\n<p>There are two possibilities………</p>\n<ul>\n<li style=\"text-align: left;\">\n<h3>The production of bile acids, by the liver, is compromised.</h3>\n</li>\n</ul>\n<p><img class=\"aligncenter size-full wp-image-19272\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/liver-not-making-bile-acids.png\" alt=\"liver not producing bile acids\" width=\"660\" height=\"358\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/liver-not-making-bile-acids.png 660w, https://betterbodychemistry.com/wp-content/uploads/2019/03/liver-not-making-bile-acids-300x163.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/03/liver-not-making-bile-acids-300x163@2x.png 600w\" sizes=\"(max-width: 660px) 100vw, 660px\" /></p>\n<p> </p>\n<ul>\n<li>\n<h3>The bile acids that are being produced, are not being recycled adequately.</h3>\n</li>\n</ul>\n<p><img class=\"aligncenter size-full wp-image-19273\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/intestine-not-recirculating-bile-acids.png\" alt=\"enterohepatic circulation disrupted\" width=\"660\" height=\"379\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/intestine-not-recirculating-bile-acids.png 660w, https://betterbodychemistry.com/wp-content/uploads/2019/03/intestine-not-recirculating-bile-acids-300x172.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/03/intestine-not-recirculating-bile-acids-300x172@2x.png 600w\" sizes=\"(max-width: 660px) 100vw, 660px\" /></p>\n<p>The Karolinska researchers, think option two, is the problem, for most people.  Future studies will shed more light on the issue.</p>\n<p>But the take home message from this study……………</p>\n<h3 style=\"text-align: center;\">Obsessing about your cholesterol levels, is unlikely to make much difference to your risk of gallbladder disease.</h3>\n\n<div class=\"symple-box yellow none \" style=\"text-align:left; width:100%;\"> <strong>Gallbladder bile supersaturated with cholesterol in gallstone patients preferentially develops from shortage of bile acids</strong>. Journal of Lipid Research (2019) Mats Rudling, Amit Laskar and Sara Straniero</div>\n<h2>Further reading</h2>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-16245\" src=\"https://betterbodychemistry.com/wp-content/uploads/2016/07/cholesterol-numbers-tn.png\" alt=\"cholesterol number\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2016/07/cholesterol-numbers-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2016/07/cholesterol-numbers-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2016/07/cholesterol-numbers-tn-55x55.png 55w, https://betterbodychemistry.com/wp-content/uploads/2016/07/cholesterol-numbers-tn-55x55@2x.png 110w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/cholesterol/cholesterol-number/\">If your cholesterol number is a little high – DON’T WORRY</a></p>\n<p>Your cholesterol number needs to be just right and the just right number, if you don’t have high BP, is somewhere between 5 and 7 mM. It’s NOT 4 mM.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-18342\" src=\"https://betterbodychemistry.com/wp-content/uploads/2018/04/EPC-exposed-to-toxin-tn.png\" alt=\"EPC being exposed to a toxin\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2018/04/EPC-exposed-to-toxin-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2018/04/EPC-exposed-to-toxin-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2018/04/EPC-exposed-to-toxin-tn-55x55.png 55w, https://betterbodychemistry.com/wp-content/uploads/2018/04/EPC-exposed-to-toxin-tn-55x55@2x.png 110w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/heart-disease/epcs-fail-cholesterol/\">Cholesterol clogs up blood vessels because blood vessels fail</a></p>\n<p>A cell lining a blood vessel suffers a catastrophic event AND IS NOT REPLACED, because you’re short of EPCs – cholesterol then fills the leaking pipe, and so it begins.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-last symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-14349\" src=\"https://betterbodychemistry.com/wp-content/uploads/2015/03/cholesterol-keeps-sugar-gates-standing-tn.png\" alt=\"statin stopping cholesterol\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2015/03/cholesterol-keeps-sugar-gates-standing-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2015/03/cholesterol-keeps-sugar-gates-standing-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2015/03/cholesterol-keeps-sugar-gates-standing-tn-55x55.png 55w, https://betterbodychemistry.com/wp-content/uploads/2015/03/cholesterol-keeps-sugar-gates-standing-tn-55x55@2x.png 110w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/cholesterol/statins-cholesterol-sugar-levels-bad/\">Statins lower cholesterol but raise sugar levels and this is bad</a></p>\n<p>When cholesterol levels are TOO low, sugar levels rise, because, the uptake of sugar, depends on cholesterol. Too much sugar is the real cause heart disease.</p>\n</div>\n<p> </p>\n<h2 style=\"text-align: center;\"><span style=\"color: #c33035;\">Want to discover more ways to create BETTER BODY CHEMISTRY ?</span></h2>\n<div class=\'_form_1213\'></div><script type=\'text/javascript\' src=\'https://spoonfulofscience.activehosted.com/f/embed.php?id=1213&5C9179B1C14E2&nostyles=1\'></script>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/cholesterol/gallstones-cholesterol-problem/\">Gallstones are NOT a cholesterol problem</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:36:\"http://wellformedweb.org/CommentAPI/\";a:1:{s:10:\"commentRss\";a:1:{i:0;a:5:{s:4:\"data\";s:80:\"https://betterbodychemistry.com/cholesterol/gallstones-cholesterol-problem/feed/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:38:\"http://purl.org/rss/1.0/modules/slash/\";a:1:{s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:1:\"0\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}}}i:1;a:6:{s:4:\"data\";s:75:\"\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n \n \n \n \n \n \";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";s:5:\"child\";a:5:{s:0:\"\";a:7:{s:5:\"title\";a:1:{i:0;a:5:{s:4:\"data\";s:49:\"The calorie label on that packet of nuts is wrong\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"link\";a:1:{i:0;a:5:{s:4:\"data\";s:60:\"https://betterbodychemistry.com/obesity/calories-nuts-wrong/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:68:\"https://betterbodychemistry.com/obesity/calories-nuts-wrong/#respond\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:7:\"pubDate\";a:1:{i:0;a:5:{s:4:\"data\";s:31:\"Thu, 07 Mar 2019 05:35:26 +0000\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"category\";a:12:{i:0;a:5:{s:4:\"data\";s:7:\"Obesity\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:1;a:5:{s:4:\"data\";s:6:\"almond\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:2;a:5:{s:4:\"data\";s:8:\"calories\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:3;a:5:{s:4:\"data\";s:9:\"fattening\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:4;a:5:{s:4:\"data\";s:5:\"fiber\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:5;a:5:{s:4:\"data\";s:10:\"food label\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:6;a:5:{s:4:\"data\";s:9:\"magnesium\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:7;a:5:{s:4:\"data\";s:4:\"nuts\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:8;a:5:{s:4:\"data\";s:7:\"obesity\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:9;a:5:{s:4:\"data\";s:9:\"pistachos\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:10;a:5:{s:4:\"data\";s:5:\"snack\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:11;a:5:{s:4:\"data\";s:6:\"walnut\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"guid\";a:1:{i:0;a:5:{s:4:\"data\";s:40:\"https://betterbodychemistry.com/?p=19091\";s:7:\"attribs\";a:1:{s:0:\"\";a:1:{s:11:\"isPermaLink\";s:5:\"false\";}}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:11:\"description\";a:1:{i:0;a:5:{s:4:\"data\";s:368:\"<p>Nuts are considered a high calorie snack. They’re actually not. It turns out, they GOT THE CALORIE COUNT WRONG !</p>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/obesity/calories-nuts-wrong/\">The calorie label on that packet of nuts is wrong</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:32:\"http://purl.org/dc/elements/1.1/\";a:1:{s:7:\"creator\";a:1:{i:0;a:5:{s:4:\"data\";s:8:\"Dr Sandy\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:40:\"http://purl.org/rss/1.0/modules/content/\";a:1:{s:7:\"encoded\";a:1:{i:0;a:5:{s:4:\"data\";s:13357:\"<p><iframe src=\"https://www.youtube.com/embed/oOytl1_B1U4\" width=\"640\" height=\"480\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"></iframe></p>\n\n<p>Click to listen to the audio…</p>\n<p><script type=\"text/javascript\" src=\"//spoonfulofscience.audello.com/player/Y291bnRpbmctbnV0LWNhbG9yaWVzLm1wMw==/?container=audello-3TEBUMYKT5\" async></script></p>\n<div id=\"audello-3TEBUMYKT5\" class=\"audello-player audello-file\" data-role=\"audello-file\" data-audello-id=\"Y291bnRpbmctbnV0LWNhbG9yaWVzLm1wMw==\"></div>\n<h1 style=\"text-align: center;\">Nuts are NOT as fattening as you think !</h1>\n<div id=\"attachment_19248\" style=\"width: 412px\" class=\"wp-caption alignright\"><img class=\"size-full wp-image-19248\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/calorie-count-of-nuts-fb.jpg\" alt=\"counting the calories of nuts\" width=\"402\" height=\"636\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/calorie-count-of-nuts-fb.jpg 402w, https://betterbodychemistry.com/wp-content/uploads/2019/03/calorie-count-of-nuts-fb-190x300.jpg 190w, https://betterbodychemistry.com/wp-content/uploads/2019/03/calorie-count-of-nuts-fb-190x300@2x.jpg 380w\" sizes=\"(max-width: 402px) 100vw, 402px\" /><p class=\"wp-caption-text\">Nuts are considered a high calorie snack. They’re actually not. It turns out, they GOT THE CALORIE COUNT WRONG !</p></div>\n<p>I am not a big calorie counter…….</p>\n<p style=\"text-align: center;\">So the fact that nuts are a high calorie snack, doesn’t phase me.</p>\n<h3 style=\"text-align: center;\">I eat nuts, EVERYDAY ! I LOVE THEM.</h3>\n<p>In fact, the thing that curtails my nut consumption, is the noxious fumes I emit, when I have too many, not the calorie count.</p>\n<p style=\"text-align: center;\">But, I know for many people………. the CALORIE COUNT, is what keeps nuts, off their menu.</p>\n<p style=\"text-align: center;\"><em>And the price. Eish ! They are rather expensive.</em></p>\n<p>What if I told you, they actually NOT that high in calories. Seriously…..</p>\n<h4 style=\"text-align: center;\"> They GOT THE CALORIE COUNT WRONG !</h4>\n<h2><span style=\"color: #f21f02;\"><strong>Calorie labels</strong></span></h2>\n<p>Are based on calculations, not actual measurements.</p>\n<p>If you realize what a palaver it is to actually measure the calorie count of a food, you quickly realize, why for most foods, it’s calculated.</p>\n<p>The calculation is based on Atwater factors…..</p>\n<h2><span style=\"color: #f21f02;\"><strong>Calculating the calorie count</strong></span></h2>\n<p>Which really just means, the amount of protein, fat and carbohydrates is measured. It is assumed that a fixed percentage of these macronutrients, will be digested.</p>\n<p>In the case of nuts………..</p>\n<p style=\"text-align: center;\">It is assume 78 % of the protein, 90 % of the fat and 97 % of the carbs, will be digested.</p>\n<p style=\"text-align: center;\">The rest will be pooped out.</p>\n<p>But are nuts all that digestible ?</p>\n<p>This is what a team of researchers, based at Beltsville Human Nutrition Research Centre in MD, set out to discover.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Nuts to volunteer ?</strong></span></h2>\n<p>They enlisted the help of 18 PLUCKY healthy volunteers and fed them cashew nuts.</p>\n<p>Plucky…………….</p>\n<p style=\"text-align: center;\">These guys had to collect all their poop and urine, every day for 7 days, on 2 separate occasions.</p>\n<h2><span style=\"color: #f21f02;\"><strong>To nut or not to nut</strong></span></h2>\n<p>The first occasion, served as the baseline, during this time, NO CASHEW nuts were consumed, the second occasion, corresponded with CASHEW snacking.</p>\n<p style=\"text-align: center;\">The size of the cashew nut snack was 42 g per day, that’s a generous handful.</p>\n<p style=\"text-align: center;\"><em>21 g at breakfast and 21 g at dinner.</em></p>\n<h2><span style=\"color: #f21f02;\"><strong>Calorie counting </strong></span></h2>\n<p>Everything else was kept pretty much the same,  with all the meals and snacks, being provided by the research centre.</p>\n<p><em>NOTE : Minor adjustments were made to ensure, the total calorie count was the same, on both occasions. These adjustments were individualized, so people did not lose or gain weight, during the study. </em></p>\n<h2><span style=\"color: #f21f02;\"><strong>Cashew nut digestion</strong></span></h2>\n<p>The team calculated what went in…………..in terms of the fat, nitrogen, energy and ash content.</p>\n<h3 style=\"text-align: center;\">Then they calculated what came out.</h3>\n<p><img class=\"aligncenter size-full wp-image-19249\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/doing-the-nut-calorie-count.png\" alt=\"how much nut goes in and out\" width=\"675\" height=\"365\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/doing-the-nut-calorie-count.png 675w, https://betterbodychemistry.com/wp-content/uploads/2019/03/doing-the-nut-calorie-count-300x162.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/03/doing-the-nut-calorie-count-300x162@2x.png 600w\" sizes=\"(max-width: 675px) 100vw, 675px\" /></p>\n<h3 style=\"text-align: center;\">Both ends !</h3>\n<p>They used this information, to determine just how much of the cashew nut snack was assimilated, for each subject.</p>\n<p>Here are the results…</p>\n<h2><span style=\"color: #f21f02;\"><strong>Counting cashew calories</strong></span></h2>\n<p>There were differences between individuals. Some people were good cashew nut digesters, some, not so much.</p>\n<h3 style=\"text-align: center;\">But, no one digested the nuts, as well as PREDICTED.</h3>\n<div id=\"attachment_19250\" style=\"width: 690px\" class=\"wp-caption aligncenter\"><img class=\"size-full wp-image-19250\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/nut-calorie-count-graph.png\" alt=\"nut calorie count graph\" width=\"680\" height=\"313\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/nut-calorie-count-graph.png 680w, https://betterbodychemistry.com/wp-content/uploads/2019/03/nut-calorie-count-graph-300x138.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/03/nut-calorie-count-graph-300x138@2x.png 600w\" sizes=\"(max-width: 680px) 100vw, 680px\" /><p class=\"wp-caption-text\">Energy value of cashew nuts. Subject # indicates data from an individual subject; each subject<br />number indicates a different individual. Copyright 2018 Baer & Novotny</p></div>\n<p>The “redâ€� line shows what was expected, based on Atwater factors. In reality, the number of calories was on average, 16 % lower.</p>\n<p>Yah ! Cashew nuts aren’t so fattening…..</p>\n<h2><span style=\"color: #f21f02;\"><strong>I</strong><strong>t’s a nut thing</strong></span></h2>\n<p>It’s a nut thing, not a cashew phenomenon.</p>\n<p>The same thing happens when you eat</p>\n<ul>\n<li>Walnuts</li>\n<li>Almonds</li>\n<li>Pistachios</li>\n</ul>\n<p>NOTE : In the case of pistachios the difference is quite small, only 5 %. In walnuts and almonds, the difference is in the order of 20 – 25 %.</p>\n<p><img class=\"alignleft size-full wp-image-19251\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/cracking-nut-cells-open.png\" alt=\"enzyme struggling to crack open a nut\" width=\"364\" height=\"221\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/cracking-nut-cells-open.png 364w, https://betterbodychemistry.com/wp-content/uploads/2019/03/cracking-nut-cells-open-300x182.png 300w\" sizes=\"(max-width: 364px) 100vw, 364px\" />The calories are ………………….</p>\n<h2><span style=\"color: #f21f02;\"><strong>Stuck inside</strong></span></h2>\n<p>As plants, nut cells have a robust cell wall. Popping this open, is a little challenging for us humans.</p>\n<p>It does happen…………..</p>\n<h3 style=\"text-align: center;\">But the contents of every nut cell, is not released.<img class=\"alignright size-full wp-image-19253\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/poop-smelling-nutty-s.png\" alt=\"nutty smelling poop\" width=\"291\" height=\"300\" /></h3>\n<h3 style=\"text-align: center;\">Many whole  nut cells make it out of the gut, still intact.</h3>\n<p>The more processed the nut is, the more likely it is that the cell wall will break somewhere along the digestive tract …………..</p>\n<p>Allowing the contents to be digested.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Processing helps</strong></span></h2>\n<p>Roasting nuts, increases the brittleness of the nut, making “chompingâ€� on the nut, a little more effective, this means smaller particles are created.</p>\n<h3 style=\"text-align: center;\">A smaller particle is easier to digest.</h3>\n<p>Grinding up the nuts, to make a nut butter, will also result in smaller particles and increased nutrient digestibility.</p>\n<p>But, when all is said and done…………..</p>\n<h2><span style=\"color: #f21f02;\"><strong>Rethink nut snacks</strong></span></h2>\n<p> </p>\n<p>Nuts are not as calorie dense, as we’ve been led to believe.</p>\n<h3 style=\"text-align: center;\">They’re pretty satiating and full of nutrients.</h3>\n<p>Some of their claims to fame : they’re high in magnesium, vitamin E and fiber ; all of these are nutrients, we’re often not getting enough of.</p>\n<h2 style=\"text-align: center;\">So, don’t be afraid to include nuts in your diet.</h2>\n<p><img class=\"aligncenter size-full wp-image-19254\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/snack-on-nuts-2.jpg\" alt=\"row of cartoon nuts\" width=\"658\" height=\"324\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/03/snack-on-nuts-2.jpg 658w, https://betterbodychemistry.com/wp-content/uploads/2019/03/snack-on-nuts-2-300x148.jpg 300w, https://betterbodychemistry.com/wp-content/uploads/2019/03/snack-on-nuts-2-300x148@2x.jpg 600w\" sizes=\"(max-width: 658px) 100vw, 658px\" /></p>\n\n<div class=\"symple-box yellow none \" style=\"text-align:left; width:100%;\"> <strong><a href=\"https://doi.org/10.3390/nu11010033/\">Metabolizable Energy from Cashew Nuts is Less than that Predicted by Atwater Factors.</a> </strong> Nutrients (2018) 11(1). pii: E33. David J. Baer and Janet A. Novotny.</div>\n<h2>Further reading</h2>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-13990\" src=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/pistachio-nuts-improve-heart-resilience-tn.png\" alt=\"pistachio nuts improve heart resilience\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/pistachio-nuts-improve-heart-resilience-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2014/09/pistachio-nuts-improve-heart-resilience-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2014/09/pistachio-nuts-improve-heart-resilience-tn-55x55.png 55w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/heart-disease/stressed-nibbles/\">If you must nibble when stressed, nibble on something de-stressing</a></p>\n<p>Stress brings out the need to nibble, for a diabetic, the choices are limited, so what should a diabetic snack on ?</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-3455\" src=\"https://betterbodychemistry.com/wp-content/uploads/2011/06/walnut-winning-the-nut-contest-tn.png\" alt=\"walnut winning the nut contest\" width=\"125\" height=\"125\" /></p>\n<p><a href=\"http://betterbodychemistry.com/antioxidants/crack-open-walnut-beat-heart-disease/\">Crack open a walnut to beat heart disease</a></p>\n<p>Numerous studies have linked regular nut consumption to decreased risk of cardiovascular disease. All nuts have talent but the nut of nuts is the walnut.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-last symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-3247\" src=\"https://betterbodychemistry.com/wp-content/uploads/2011/06/gut-bacteria-being-fed-almonds-tn.png\" alt=\"gut bacteria being fed almonds\" width=\"125\" height=\"125\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/bacteria/almonds-dog-biscuits/\">Almonds are like dog biscuits for bacteria</a></p>\n<p>You feed your dog specifically formulated biscuits so it has all the nutrients a dog needs to be healthy but your gut bacteria have to keep going on leftovers.</p>\n</div>\n<p> </p>\n<h2 style=\"text-align: center;\"><span style=\"color: #c33035;\">Want to discover more ways to create BETTER BODY CHEMISTRY ?</span></h2>\n<div class=\'_form_1213\'></div><script type=\'text/javascript\' src=\'https://spoonfulofscience.activehosted.com/f/embed.php?id=1213&5C9179B1C6940&nostyles=1\'></script>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/obesity/calories-nuts-wrong/\">The calorie label on that packet of nuts is wrong</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:36:\"http://wellformedweb.org/CommentAPI/\";a:1:{s:10:\"commentRss\";a:1:{i:0;a:5:{s:4:\"data\";s:65:\"https://betterbodychemistry.com/obesity/calories-nuts-wrong/feed/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:38:\"http://purl.org/rss/1.0/modules/slash/\";a:1:{s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:1:\"0\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}}}i:2;a:6:{s:4:\"data\";s:66:\"\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n \n \n \n \n \n \";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";s:5:\"child\";a:5:{s:0:\"\";a:7:{s:5:\"title\";a:1:{i:0;a:5:{s:4:\"data\";s:31:\"Endotoxin in insulin resistance\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"link\";a:1:{i:0;a:5:{s:4:\"data\";s:64:\"https://betterbodychemistry.com/ir/endotoxin-insulin-resistance/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:72:\"https://betterbodychemistry.com/ir/endotoxin-insulin-resistance/#respond\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:7:\"pubDate\";a:1:{i:0;a:5:{s:4:\"data\";s:31:\"Thu, 28 Feb 2019 05:35:44 +0000\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"category\";a:9:{i:0;a:5:{s:4:\"data\";s:2:\"IR\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:1;a:5:{s:4:\"data\";s:11:\"endotoxemia\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:2;a:5:{s:4:\"data\";s:9:\"endotoxin\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:3;a:5:{s:4:\"data\";s:18:\"insulin resistance\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:4;a:5:{s:4:\"data\";s:23:\"intestinal permeability\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:5;a:5:{s:4:\"data\";s:9:\"leaky gut\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:6;a:5:{s:4:\"data\";s:18:\"lipopolysaccharide\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:7;a:5:{s:4:\"data\";s:22:\"low grade inflammation\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:8;a:5:{s:4:\"data\";s:3:\"LPS\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"guid\";a:1:{i:0;a:5:{s:4:\"data\";s:40:\"https://betterbodychemistry.com/?p=19215\";s:7:\"attribs\";a:1:{s:0:\"\";a:1:{s:11:\"isPermaLink\";s:5:\"false\";}}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:11:\"description\";a:1:{i:0;a:5:{s:4:\"data\";s:420:\"<p>We look at endotoxin, gram negative bacteria’s dirty laundry. It shouldn’t be a problem, but because the gut becomes “leakyâ€� in the insulin resistant, it is. </p>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/ir/endotoxin-insulin-resistance/\">Endotoxin in insulin resistance</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:32:\"http://purl.org/dc/elements/1.1/\";a:1:{s:7:\"creator\";a:1:{i:0;a:5:{s:4:\"data\";s:8:\"Dr Sandy\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:40:\"http://purl.org/rss/1.0/modules/content/\";a:1:{s:7:\"encoded\";a:1:{i:0;a:5:{s:4:\"data\";s:14558:\"<p><iframe src=\"https://www.youtube.com/embed/54SSErNy2i4\" width=\"640\" height=\"480\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"></iframe></p>\n\n<p>Click to listen to the audio…</p>\n<p><script type=\"text/javascript\" src=\"//spoonfulofscience.audello.com/player/ZW5kb3RveGluLWluLXRoZS1pbnN1bGluLXJlc2lzdGFudC5tcDM=/?container=audello-0FEX43RG2I\" async></script></p>\n<div id=\"audello-0FEX43RG2I\" class=\"audello-player audello-file\" data-role=\"audello-file\" data-audello-id=\"ZW5kb3RveGluLWluLXRoZS1pbnN1bGluLXJlc2lzdGFudC5tcDM=\"></div>\n<p><a href=\"https://prezi.com/view/q1wWZBpFO2x6tbGY9m2Y/\">Click here</a> to view the prezi.</p>\n<p>When you’re insulin resistant, that is, you’ve got  metabolic syndrome, pretty much every chemical in the body is NOT QUITE RIGHT. Some are up. Some are down. Few are actually at physiologically NORMAL levels.</p>\n<p>Traditionally the focus is on the big guns.</p>\n<ul>\n<li>Sugar</li>\n<li>Insulin</li>\n<li>And cholesterol</li>\n</ul>\n<p>In this series, we  take a look at some of the other players.</p>\n<p>Who they are, what they’re up to and how they’re part of the state of insulin resistance.</p>\n<h1 style=\"text-align: center;\"><strong>Endotoxin in the insulin resistant</strong></h1>\n<p>In metabolic syndrome, endotoxin is fractionally up.</p>\n<h2><span style=\"color: #f21f02;\">It’s NOT septicaemia</span></h2>\n<p>We’re talking somewhere between 3-5 times higher, than normal. This contrasts with the situation of sepsis, which is when you have a raging uncontrolled infection, under these circumstances, endotoxin levels can be a 100 times higher than normal.</p>\n<p style=\"text-align: center;\">In this situation, calling it a toxin, is an accurate description.</p>\n<p><img class=\"aligncenter size-full wp-image-19216\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/septisemia.png\" alt=\"endotoxin in septicaemia\" width=\"586\" height=\"322\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/septisemia.png 586w, https://betterbodychemistry.com/wp-content/uploads/2019/02/septisemia-300x165.png 300w\" sizes=\"(max-width: 586px) 100vw, 586px\" /></p>\n<h3 style=\"text-align: center;\">Sepsis is life threatening.</h3>\n<h2><span style=\"color: #f21f02;\">On guard, not acting crazy</span></h2>\n<p>The immune system is in an absolute frenzy and that frenzy can create lots of collateral damage. But at 3-5 times higher…………. the situation is different.</p>\n<h3 style=\"text-align: center;\">The immune system is on alert, but it won’t be behaving as an out of control, maniac.</h3>\n<p>The polite way to describe, the immune system’s temperament, is metabolic endotoxemia.  It is a toxic situation.  But going so far as to describe the chemical as toxin – is probably a bit melodramatic.</p>\n<h2><span style=\"color: #f21f02;\">Lipopolysaccharide aka endotoxin</span></h2>\n<p>The chemical in question, is actually part of the cell wall, of one of the tribes of bacteria that live in the gut.  When it’s part of a gram negative bacteria’s anatomy, it’s referred to as lipopolysaccharide or LPS for short.</p>\n<p style=\"text-align: center;\">The little guys need it, to keep themselves together.</p>\n<p><img class=\"aligncenter size-full wp-image-19217\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/lps-shedding-in-gut.png\" alt=\"LPS shedding in the gut\" width=\"522\" height=\"360\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/lps-shedding-in-gut.png 522w, https://betterbodychemistry.com/wp-content/uploads/2019/02/lps-shedding-in-gut-300x207.png 300w\" sizes=\"(max-width: 522px) 100vw, 522px\" /></p>\n<p style=\"text-align: center;\">And they shed it, into the gut, on a continuous basis.</p>\n<p style=\"text-align: center;\">It is estimated that at any given moment in time, there is about 1 g of LPS, inside the gut.</p>\n<h2 style=\"text-align: center;\">It’s presence is NOT a big deal.</h2>\n<h2><span style=\"color: #f21f02;\">A calling card</span></h2>\n<p>In fact, it’s quite useful – it alerts our immune system to the presence of bacteria and ensures, the necessary defences and precautions are in place, allowing for a peaceful co-existence, between MAN and BEAST.</p>\n<p>Where things get tricky……………</p>\n<h2><span style=\"color: #f21f02;\">Beyond the gut</span></h2>\n<p>Is “itemsâ€� move from inside the gut, into the body. Now most of the “itemsâ€� are useful, think sugar, caffeine and calcium, but less desirable things, can also make the trip.</p>\n<h1 style=\"text-align: center;\">LPS is one such item.</h1>\n<p><img class=\"aligncenter size-full wp-image-19218\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/absorption.png\" alt=\"absorption beyond the gut\" width=\"648\" height=\"360\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/absorption.png 648w, https://betterbodychemistry.com/wp-content/uploads/2019/02/absorption-300x167.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/02/absorption-300x167@2x.png 600w\" sizes=\"(max-width: 648px) 100vw, 648px\" /></p>\n<p>It arrives in the liver and it’s presence makes liver immune cells NERVOUS. But, generally speaking, it’s quickly cleared up and things return to normal.</p>\n<p>Except in people who are insulin resistance….</p>\n<h2><span style=\"color: #f21f02;\">When the defences fail</span></h2>\n<p>Small amount of LPS, slip past the defences.  Leaving the immune system a bit twitchy.  The term describe this is low grade inflammation.</p>\n<p><img class=\"aligncenter size-full wp-image-19219\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/low-grade-inflammation.png\" alt=\"low grade inflammation\" width=\"575\" height=\"349\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/low-grade-inflammation.png 575w, https://betterbodychemistry.com/wp-content/uploads/2019/02/low-grade-inflammation-300x182.png 300w\" sizes=\"(max-width: 575px) 100vw, 575px\" /></p>\n<h2 style=\"text-align: center;\">Low grade inflammation makes for bad body chemistry.</h2>\n<p>It is implicated in most age associated diseases…</p>\n<h2><span style=\"color: #f21f02;\">Why do the defences fail ?</span></h2>\n<p>There are a couple of possibilities……….</p>\n<ul>\n<li>The defences, in the gut, aren’t working properly.</li>\n<li>There is too much, of the “wrong kindâ€� of LPS in the gut – overwhelming the normal defences.</li>\n<li>The intestinal barrier is more “leakyâ€� than usual  e. it is allowing more LPS through, overwhelming the normal defences.</li>\n</ul>\n<p><img class=\"aligncenter size-full wp-image-19220\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/why-do-the-defences-fail.png\" alt=\"causes of metabolic endotoxemia\" width=\"644\" height=\"363\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/why-do-the-defences-fail.png 644w, https://betterbodychemistry.com/wp-content/uploads/2019/02/why-do-the-defences-fail-300x169.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/02/why-do-the-defences-fail-320x180@2x.png 640w, https://betterbodychemistry.com/wp-content/uploads/2019/02/why-do-the-defences-fail-320x180.png 320w, https://betterbodychemistry.com/wp-content/uploads/2019/02/why-do-the-defences-fail-300x169@2x.png 600w\" sizes=\"(max-width: 644px) 100vw, 644px\" /></p>\n<h3 style=\"text-align: center;\">There is science, to support all three.</h3>\n<p>And no doubt, high insulin levels are a contributing factor….</p>\n<h2><span style=\"color: #f21f02;\">Protecting the intestinal barrier</span></h2>\n<p>The take home message, you’ve got to do what you can to keep your gut, strong and healthy.</p>\n<p>How do you do this ?</p>\n<p style=\"text-align: center;\">The place to start is to watch when and what  you consume and cultivate the “rightâ€� microflora.</p>\n<p style=\"text-align: center;\"><em>For tips and strategies to help you create the “right” microflora, visit our <a href=\"http://www.betterbodychemistry.com/good-bacteria/\">microbiome library page.</a></em></p>\n<p><img class=\"aligncenter size-full wp-image-19221\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/whatch-what-and-when-you-eat.png\" alt=\"protecting the barrier\" width=\"479\" height=\"314\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/whatch-what-and-when-you-eat.png 479w, https://betterbodychemistry.com/wp-content/uploads/2019/02/whatch-what-and-when-you-eat-300x197.png 300w\" sizes=\"(max-width: 479px) 100vw, 479px\" /></p>\n<p>Substances that can be particularly problematic include gluten, alcohol and food additives, particularly emulsifiers, these are found in processed foods.</p>\n<p><em>NOTE : LPS is just one of the hundreds of chemicals in the body that are amiss, when you’re suffering from metabolic syndrome. You can learn about some of the other players, in the <a href=\"https://betterbodychemistry.com/insulin-resistance-system/\">Ups and Downs of Insulin Resistance</a> series.</em></p>\n\n<div class=\"symple-box yellow none \" style=\"text-align:left; width:100%;\"> <a href=\"https://doi.org/10.1089/met.2014.1504\"><strong>Endotoxemia of metabolic syndrome: a pivotal mediator of meta-inflammation.</strong></a> Metab Syndr Relat Disord. (2014)12(9):454-6.  I Jialal, U Rajamani.</p>\n<p><a href=\"https://doi.org/10.1152/ajpgi.00098.2016\"><strong>Gastrointestinal and hepatic mechanisms limiting entry and dissemination of lipopolysaccharide into the systemic circulation. </strong> </a>Am J Physiol Gastrointest Liver Physiol (2016) 311: G1–G15. Mathilde Guerville and Gaëlle Boudry</p>\n<p>I<a href=\"https://doi.org/10.1186/s12876-014-0189-7\"><strong>ntestinal permeability – a new target for disease prevention and therapy.</strong></a> BMC Gastroenterology (2014) 14:189. Stephan C Bischoff , Giovanni Barbara , Wim Buurman, Theo Ockhuizen, Jörg-Dieter Schulzke, Matteo Serino, Herbert Tilg,  Alastair Watson, and Jerry M Wells.</div>\n<h2>Further reading</h2>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><a href=\"http://expectingmagic.co.za/wp-content/uploads/2014/07/horsing-around-can-calm-cortisol-tn.png\"><img class=\"aligncenter size-full wp-image-16543\" src=\"https://betterbodychemistry.com/wp-content/uploads/2016/09/iap-picking-up-endotoxin-tn.png\" alt=\"IAP picking up endotoxin\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2016/09/iap-picking-up-endotoxin-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2016/09/iap-picking-up-endotoxin-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2016/09/iap-picking-up-endotoxin-tn-55x55.png 55w, https://betterbodychemistry.com/wp-content/uploads/2016/09/iap-picking-up-endotoxin-tn-55x55@2x.png 110w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></a></p>\n<p><a href=\"http://www.betterbodychemistry.com/diabetes/iap-type-2-diabetes/\">I am at risk of type 2 diabetes – give me more IAP please</a></p>\n<p>Endotoxin, a bacterial waste product is partly to blame for the inflammation of obesity, but why is it accumulating ? There is a lack of IAP to clean it up.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><a href=\"http://expectingmagic.co.za/wp-content/uploads/2014/07/horsing-around-can-calm-cortisol-tn.png\"><img class=\"aligncenter size-full wp-image-15096\" src=\"https://betterbodychemistry.com/wp-content/uploads/2015/11/omega-3-helping-the-gut-clean-up-tn.png\" alt=\"omega 3 helping the gut clean up crew\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2015/11/omega-3-helping-the-gut-clean-up-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2015/11/omega-3-helping-the-gut-clean-up-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2015/11/omega-3-helping-the-gut-clean-up-tn-55x55.png 55w, https://betterbodychemistry.com/wp-content/uploads/2015/11/omega-3-helping-the-gut-clean-up-tn-55x55@2x.png 110w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></a></p>\n<p><a href=\"http://www.betterbodychemistry.com/obesity/stop-low-grade-inflammation/\">A little house keeping in the colon, will help stop inflammation</a></p>\n<p>Endotoxemia (LPS) is contributes to the low grade inflammation associated with obesity – but it shouldn’t be circulating, house keeping should sweep it away</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-last symple-all\">\n<p style=\"text-align: center;\"><a href=\"http://expectingmagic.co.za/wp-content/uploads/2014/07/horsing-around-can-calm-cortisol-tn.png\"><img class=\"aligncenter size-full wp-image-17002\" src=\"https://betterbodychemistry.com/wp-content/uploads/2017/01/bacteria-eating-gut-cell-lining-tn.png\" alt=\"bacteria eating gut cell lining\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2017/01/bacteria-eating-gut-cell-lining-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2017/01/bacteria-eating-gut-cell-lining-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2017/01/bacteria-eating-gut-cell-lining-tn-55x55.png 55w, https://betterbodychemistry.com/wp-content/uploads/2017/01/bacteria-eating-gut-cell-lining-tn-55x55@2x.png 110w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></a></p>\n<p><a href=\"http://www.betterbodychemistry.com/bacteria/gut-bacteria-eat-house-home/\">Don’t let your gut bacteria eat you out of house and home</a></p>\n<p>When a gut bacteria can’t find something fibrous to chew, it will just eat something else. Good for the bacteria, but potentially dangerous for you !</p>\n</div>\n<p> </p>\n<h2 style=\"text-align: center;\"><span style=\"color: #c33035;\">Want to discover more ways to create BETTER BODY CHEMISTRY ?</span></h2>\n<div class=\'_form_1213\'></div><script type=\'text/javascript\' src=\'https://spoonfulofscience.activehosted.com/f/embed.php?id=1213&5C9179B1CBD50&nostyles=1\'></script>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/ir/endotoxin-insulin-resistance/\">Endotoxin in insulin resistance</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:36:\"http://wellformedweb.org/CommentAPI/\";a:1:{s:10:\"commentRss\";a:1:{i:0;a:5:{s:4:\"data\";s:69:\"https://betterbodychemistry.com/ir/endotoxin-insulin-resistance/feed/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:38:\"http://purl.org/rss/1.0/modules/slash/\";a:1:{s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:1:\"0\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}}}i:3;a:6:{s:4:\"data\";s:66:\"\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n \n \n \n \n \n \";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";s:5:\"child\";a:5:{s:0:\"\";a:7:{s:5:\"title\";a:1:{i:0;a:5:{s:4:\"data\";s:34:\"The chemistry behind angry moments\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"link\";a:1:{i:0;a:5:{s:4:\"data\";s:76:\"https://betterbodychemistry.com/heart-disease/bacteria-dispatch-letter-bomb/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:85:\"https://betterbodychemistry.com/heart-disease/bacteria-dispatch-letter-bomb/#comments\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:7:\"pubDate\";a:1:{i:0;a:5:{s:4:\"data\";s:31:\"Wed, 20 Feb 2019 18:00:09 +0000\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"category\";a:9:{i:0;a:5:{s:4:\"data\";s:13:\"Heart disease\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:1;a:5:{s:4:\"data\";s:10:\"adrenaline\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:2;a:5:{s:4:\"data\";s:15:\"adrenaline rush\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:3;a:5:{s:4:\"data\";s:5:\"angry\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:4;a:5:{s:4:\"data\";s:16:\"atheroscleorisis\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:5;a:5:{s:4:\"data\";s:8:\"bacteria\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:6;a:5:{s:4:\"data\";s:10:\"dispersion\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:7;a:5:{s:4:\"data\";s:12:\"heart attack\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:8;a:5:{s:4:\"data\";s:6:\"stress\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"guid\";a:1:{i:0;a:5:{s:4:\"data\";s:39:\"http://betterbodychemistry.com/?p=13807\";s:7:\"attribs\";a:1:{s:0:\"\";a:1:{s:11:\"isPermaLink\";s:5:\"false\";}}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:11:\"description\";a:1:{i:0;a:5:{s:4:\"data\";s:415:\"<p>Bacteria need iron to grow, so iron levels are ALWAYS kept low, except during STRESSFUL moments, when iron is made available……. bacteria come out to play</p>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/heart-disease/bacteria-dispatch-letter-bomb/\">The chemistry behind angry moments</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:32:\"http://purl.org/dc/elements/1.1/\";a:1:{s:7:\"creator\";a:1:{i:0;a:5:{s:4:\"data\";s:8:\"Dr Sandy\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:40:\"http://purl.org/rss/1.0/modules/content/\";a:1:{s:7:\"encoded\";a:1:{i:0;a:5:{s:4:\"data\";s:14066:\"<p style=\"text-align: center;\"><iframe src=\"//www.youtube.com/embed/ZHOx57-iw3k\" width=\"640\" height=\"480\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"></iframe></p>\n\n<p>Click to listen to the audio…<br />\n<script type=\"text/javascript\" src=\"//spoonfulofscience.audello.com/player/dGFudHJ1bXMtYW5kLWlyb24ubXAz/?container=audello-BKNGH96GYP\" async></script></p>\n<div id=\"audello-BKNGH96GYP\" class=\"audello-player audello-file\" data-role=\"audello-file\" data-audello-id=\"dGFudHJ1bXMtYW5kLWlyb24ubXAz\"></div>\n<p> </p>\n<h1 style=\"text-align: center;\">The chemistry behind angry moments</h1>\n<div id=\"attachment_19206\" style=\"width: 412px\" class=\"wp-caption alignright\"><img class=\"size-full wp-image-19206\" src=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/adrenaline-kicking-up-a-storm-2.png\" alt=\"adrenaline kicking up a storm\" width=\"402\" height=\"455\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/adrenaline-kicking-up-a-storm-2.png 402w, https://betterbodychemistry.com/wp-content/uploads/2014/09/adrenaline-kicking-up-a-storm-2-265x300.png 265w\" sizes=\"(max-width: 402px) 100vw, 402px\" /><p class=\"wp-caption-text\">Bacteria need iron to grow, so iron levels are ALWAYS kept low, except during STRESSFUL moments, when iron is made available……. bacteria come out to play</p></div>\n<p>The idea that being seriously “STRESSEDâ€� – read A-N-G-R-Y, leads to heart attacks is not NEW.</p>\n<p style=\"text-align: left;\"> In fact, stats suggest the odds of suffering a heart attack….</p>\n<h3 style=\"text-align: center;\">DOUBLES, two hours after an episode of ANGER.</h3>\n<h2><span style=\"color: #f21f02;\"><strong>What’s with the two hour window ?</strong></span></h2>\n<p>Two hours ?  Why not straight away ?  After all, it is in the moment that you unleash the biochemical storm that sees you</p>\n<ul>\n<li>Shake uncontrollably</li>\n<li>Turn red in the face</li>\n<li>Shoot your blood pressure reading into the stratosphere</li>\n</ul>\n<h2><span style=\"color: #f21f02;\"><strong>The calm before the storm</strong></span></h2>\n<p>Two hours later, an uneasy calm has usually returned – most of us can’t sustain that level of angry for 2 hours.</p>\n<p style=\"text-align: center;\"><strong>At the two hour mark,  YOUR biochemistry should be rebounding back to “NORMALâ€�.</strong></p>\n<p>Binghamton University researchers, have uncovered why the fall out, from the explosive moment shows this two hour time delay.</p>\n<h2><span style=\"color: #f21f02;\"><strong>The chemistry of angry moments</strong></span></h2>\n<p>An angry / STRESSFUL moment manifests with an instantaneous flood of adrenaline….</p>\n<h3 style=\"text-align: center;\">Adrenaline’s  purpose, is  to supercharge you, enough to SURVIVE a close encounter.</h3>\n<p><img class=\"aligncenter size-full wp-image-19208\" src=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/woolly-mammoth-in-a-suit.png\" alt=\"woolly mammoth in a suit\" width=\"563\" height=\"309\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/woolly-mammoth-in-a-suit.png 563w, https://betterbodychemistry.com/wp-content/uploads/2014/09/woolly-mammoth-in-a-suit-300x165.png 300w\" sizes=\"(max-width: 563px) 100vw, 563px\" /></p>\n<p>Mother Nature is thinking the close encounter might be a woolly mammoth or other great beast that could eat you for dinner, but the same programme runs if the stressor is your boss, the bank or the taxi driver.</p>\n<h2><span style=\"color: #f21f02;\"><strong>I will survive</strong></span></h2>\n<p>For the most part, SURVIVAL, depends on you being able to stand your ground or run like hell – hence the need for you to be a SUPERCHARGED version of YOU.</p>\n<h2 style=\"text-align: center;\">The objective is to survive the moment.</h2>\n<p>Hence it is a BIG FLOOD of adrenaline, and then recovery. The excess adrenaline is quickly mopped up and things slowly return to NORMAL.</p>\n<p>Well that’s what happens in the body, but deep inside the blood vessels, it is another story…..</p>\n<h2><span style=\"color: #f21f02;\"><strong>You rocked their world</strong></span></h2>\n<p>Among the cells impacted by the adrenaline rush, are the bacteria clinging to the sides of your blood vessels.</p>\n<h2 style=\"text-align: center;\">They experience an AWAKENING.</h2>\n<p>Yip, maybe you didn’t know, but blood vessels have a collection of bacteria squatters, that are tucked deep inside the arterial plaques associated with atherosclerosis.</p>\n<p>Here is a CSLM image, from this study, showing a carotid arterial plaque.</p>\n<div id=\"attachment_19207\" style=\"width: 584px\" class=\"wp-caption aligncenter\"><img class=\"size-full wp-image-19207\" src=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/bacteria-inside-carotid-arterial-plaque.png\" alt=\"bacteria inside carotid arterial plaque\" width=\"574\" height=\"335\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/bacteria-inside-carotid-arterial-plaque.png 574w, https://betterbodychemistry.com/wp-content/uploads/2014/09/bacteria-inside-carotid-arterial-plaque-300x175.png 300w\" sizes=\"(max-width: 574px) 100vw, 574px\" /><p class=\"wp-caption-text\">CSLM image showing a carotid arterial plaque from a patient. © 2014 Lanter et al</p></div>\n<p style=\"text-align: center;\">The little red specs, indicate a bacterial presence.</p>\n<h2><span style=\"color: #f21f02;\"><strong>More iron</strong></span></h2>\n<p>The flood of adrenaline changes their world…….. it releases iron.</p>\n<h3 style=\"text-align: center;\">Bacteria need iron supplies to grow and multiply.</h3>\n<p>The body “knowsâ€� this, so the body works hard to keep iron stores under lock and key.  This imposed shortage, limits the ability of bacteria to go forth and multiply.</p>\n<p>Well this is what should happen…………..</p>\n<h2><span style=\"color: #f21f02;\"><strong>No iron lockdown</strong></span></h2>\n<p>The adrenaline rush, sparked by the emotional crisis, suddenly makes iron available.</p>\n<p><img class=\"aligncenter size-full wp-image-19209\" src=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/iron-release-in-the-blood-vessel.png\" alt=\"iron release in the blood vessel\" width=\"480\" height=\"270\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/iron-release-in-the-blood-vessel.png 480w, https://betterbodychemistry.com/wp-content/uploads/2014/09/iron-release-in-the-blood-vessel-300x169.png 300w, https://betterbodychemistry.com/wp-content/uploads/2014/09/iron-release-in-the-blood-vessel-320x180.png 320w\" sizes=\"(max-width: 480px) 100vw, 480px\" /></p>\n<p style=\"text-align: center;\">And the bacteria rejoice.</p>\n<p>Since the bacteria are tucked deep inside the plaque layers, to celebrate their good fortune, they need to come out this biofilm and play.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Coming out PARTY</strong></span></h2>\n<p>A dispersion event begins….</p>\n<p>The dispersion event involves the release of enzymes, which help them to free themselves of the scaffolding that is holding them.</p>\n<p><img class=\"aligncenter size-full wp-image-19210\" src=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/a-dispersion-event.png\" alt=\"a dispersion event\" width=\"480\" height=\"270\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/a-dispersion-event.png 480w, https://betterbodychemistry.com/wp-content/uploads/2014/09/a-dispersion-event-300x169.png 300w, https://betterbodychemistry.com/wp-content/uploads/2014/09/a-dispersion-event-320x180.png 320w\" sizes=\"(max-width: 480px) 100vw, 480px\" /></p>\n<p>Unfortunately, these enzymes are by their very nature – degrading enzymes. The degradation process they initiate, can cause bits and pieces of the plaque to break free……..</p>\n<p>If the piece of plaque that breaks off,  is TOO BIG, it can lodge in a blood vessel, causing the affected blood vessel to block up, impeding oxygen flow. Tissue deprived of oxygen, rapidly begins dying.</p>\n<h2 style=\"text-align: center;\">THIS IS A HEART ATTACK !</h2>\n<h2><span style=\"color: #f21f02;\"><strong>Adrenaline the trigger</strong></span></h2>\n<p>The research team have been able to demonstrate that coming out parties happen at concentrations of norepinpherine (adrenaline), typically encountered in the body, following a “stressfulâ€� moment.</p>\n<p>In this particular experiment, <em>Pseudomonas aeruginosa, </em>one of the bacteria species associated with carotid arteries, makes moves to get free of the bonds tethering it to the biofilm, when exposed to iron.</p>\n<div id=\"attachment_19211\" style=\"width: 671px\" class=\"wp-caption aligncenter\"><img class=\"size-full wp-image-19211\" src=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/iron-causes-bacteria-to-escape-the-biofilm.png\" alt=\"graph showing how exposure to iron causes bacteria to escape biofilm\" width=\"661\" height=\"413\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/iron-causes-bacteria-to-escape-the-biofilm.png 661w, https://betterbodychemistry.com/wp-content/uploads/2014/09/iron-causes-bacteria-to-escape-the-biofilm-300x187.png 300w, https://betterbodychemistry.com/wp-content/uploads/2014/09/iron-causes-bacteria-to-escape-the-biofilm-300x187@2x.png 600w\" sizes=\"(max-width: 661px) 100vw, 661px\" /><p class=\"wp-caption-text\">Graph showing how iron encourages bacteria to escape from a biofilm. © 2014 Lanter et al</p></div>\n<h2><span style=\"color: #f21f02;\"><strong>Keep your cool</strong></span></h2>\n<p>It is easy to let things get under your skin, losing your cool and going postal, happens…..</p>\n<h3 style=\"text-align: center;\">Your iron status, can impact what kind of packages, you end up sending.</h3>\n<p style=\"text-align: center;\"><em>If you’ve got lots of iron, hanging around, the odds that you send a letter bomb, increase.</em></p>\n<p>So it is important to find ways to manage your emotions and your iron status, so that you send love letters to your heart, not letter bombs.</p>\n\n<div class=\"symple-box yellow none \" style=\"text-align:left; width:100%;\"> <a title=\"Link to journal article\" href=\"http://dx.doi.org/10.1128/mBio.01206-14\" target=\"_blank\" rel=\"noopener\"><strong>Bacteria Present in Carotid Arterial Plaques Are Found as Biofilm Deposits Which May Contribute to Enhanced Risk of Plaque Rupture</strong></a>. <em>mBio</em> (2014) 5(3):e01206-14. Bernard B. Lanter, Karin Sauer and David G. Davies.</div>\n<h2><span style=\"color: #000000;\">Further reading</span></h2>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-11523\" src=\"https://betterbodychemistry.com/wp-content/uploads/2013/02/estrogen-being-ordered-out-during-a-hysterectomy-tn.png\" alt=\"estrogen being ordered out during a hysterectomy\" width=\"125\" height=\"125\" /><br />\n<a href=\"http://www.betterbodychemistry.com/aging/brain-iron-causes-rust/\">If you want to stop brain rust – install a red robot</a></p>\n<p style=\"text-align: center;\">Iron accumulates inside the human body, especially the brain. Iron and oxygen don’t mix……. the combination leads to rusty parts and serious breakdowns.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><a href=\"http://betterbodychemistry.com/wp-content/uploads/2012/10/wakeful-resting-tn.png\"><img class=\"aligncenter size-full wp-image-11396\" src=\"https://betterbodychemistry.com/wp-content/uploads/2013/02/vampire-dracula-fixing-metabolic-syndrome-tn.png\" alt=\"vampire dracula fixing metabolic syndrome\" width=\"125\" height=\"125\" /><br />\n</a><a href=\"http://www.betterbodychemistry.com/heart-disease/high-blood-pressure-vampire/\">Suffering from high blood pressure – you need a vampire ?</a></p>\n<p style=\"text-align: center;\">If you’re suffering from metabolic syndrome – maybe it is time to let the iron out and bring down your blood pressure by giving a little blood.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-last symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-19202\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/iron-and-hepcidin-tn.png\" alt=\"hepcidin and insulin are besties\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/iron-and-hepcidin-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2019/02/iron-and-hepcidin-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2019/02/iron-and-hepcidin-tn-55x55.png 55w, https://betterbodychemistry.com/wp-content/uploads/2019/02/iron-and-hepcidin-tn-55x55@2x.png 110w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p style=\"text-align: center;\"><a href=\"https://www.betterbodychemistry.com/obesity/iron-deficiency-insulin/\">When your iron deficiency is NOT an iron deficiency</a></p>\n<p style=\"text-align: center;\">If you’ve got iron issues……….but you do eat iron containing foods, odds are your problem is NOT too little iron, but too much hepcidin, thanks to too much insulin</p>\n</div>\n<p> </p>\n<h2 style=\"text-align: center;\"><span style=\"color: #c33035;\">Want to create BETTER BODY CHEMISTRY ?</span></h2>\n<p style=\"text-align: left;\">Join our mailing list to receive weekly science based tips & strategies that will help you optimize your health and the health of your family.</p>\n<div class=\'_form_1213\'></div><script type=\'text/javascript\' src=\'https://spoonfulofscience.activehosted.com/f/embed.php?id=1213&5C9179B1D1020&nostyles=1\'></script>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/heart-disease/bacteria-dispatch-letter-bomb/\">The chemistry behind angry moments</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:36:\"http://wellformedweb.org/CommentAPI/\";a:1:{s:10:\"commentRss\";a:1:{i:0;a:5:{s:4:\"data\";s:81:\"https://betterbodychemistry.com/heart-disease/bacteria-dispatch-letter-bomb/feed/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:38:\"http://purl.org/rss/1.0/modules/slash/\";a:1:{s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:1:\"1\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}}}i:4;a:6:{s:4:\"data\";s:78:\"\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n \n \n \n \n \n \";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";s:5:\"child\";a:5:{s:0:\"\";a:7:{s:5:\"title\";a:1:{i:0;a:5:{s:4:\"data\";s:51:\"When your iron deficiency is NOT an iron deficiency\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"link\";a:1:{i:0;a:5:{s:4:\"data\";s:64:\"https://betterbodychemistry.com/obesity/iron-deficiency-insulin/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:72:\"https://betterbodychemistry.com/obesity/iron-deficiency-insulin/#respond\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:7:\"pubDate\";a:1:{i:0;a:5:{s:4:\"data\";s:31:\"Thu, 14 Feb 2019 06:27:35 +0000\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"category\";a:13:{i:0;a:5:{s:4:\"data\";s:7:\"Obesity\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:1;a:5:{s:4:\"data\";s:10:\"deficiency\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:2;a:5:{s:4:\"data\";s:7:\"dietary\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:3;a:5:{s:4:\"data\";s:12:\"dietary iron\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:4;a:5:{s:4:\"data\";s:8:\"hepcidin\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:5;a:5:{s:4:\"data\";s:7:\"insulin\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:6;a:5:{s:4:\"data\";s:18:\"insulin resistance\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:7;a:5:{s:4:\"data\";s:17:\"insulin resistant\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:8;a:5:{s:4:\"data\";s:4:\"iron\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:9;a:5:{s:4:\"data\";s:15:\"iron deficiency\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:10;a:5:{s:4:\"data\";s:10:\"iron needs\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:11;a:5:{s:4:\"data\";s:16:\"iron supplements\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:12;a:5:{s:4:\"data\";s:11:\"supplements\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"guid\";a:1:{i:0;a:5:{s:4:\"data\";s:40:\"https://betterbodychemistry.com/?p=19195\";s:7:\"attribs\";a:1:{s:0:\"\";a:1:{s:11:\"isPermaLink\";s:5:\"false\";}}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:11:\"description\";a:1:{i:0;a:5:{s:4:\"data\";s:441:\"<p>If you’ve got iron issues……….but you do eat iron containing foods, odds are your problem is NOT too little iron, but too much hepcidin, thanks to too much insulin</p>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/obesity/iron-deficiency-insulin/\">When your iron deficiency is NOT an iron deficiency</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:32:\"http://purl.org/dc/elements/1.1/\";a:1:{s:7:\"creator\";a:1:{i:0;a:5:{s:4:\"data\";s:8:\"Dr Sandy\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:40:\"http://purl.org/rss/1.0/modules/content/\";a:1:{s:7:\"encoded\";a:1:{i:0;a:5:{s:4:\"data\";s:13376:\"<p><iframe src=\"https://www.youtube.com/embed/OSdAGbuyRWQ\" width=\"640\" height=\"480\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"></iframe></p>\n\n<p>Click to listen to the audio…<br />\n<script type=\"text/javascript\" src=\"//spoonfulofscience.audello.com/player/aG93LXlvdS1jYW4tYmUtaXJvbi1kZWZpY2llbnQtZGVzcGl0ZS1jb25zdW1pbmctZGkubXAz/?container=audello-4ZN4UFB2NY\" async></script></p>\n<div id=\"audello-4ZN4UFB2NY\" class=\"audello-player audello-file\" data-role=\"audello-file\" data-audello-id=\"aG93LXlvdS1jYW4tYmUtaXJvbi1kZWZpY2llbnQtZGVzcGl0ZS1jb25zdW1pbmctZGkubXAz\"></div>\n<h2 style=\"text-align: center;\">How you can be iron deficient while consuming iron</h2>\n<p><img class=\"alignright size-full wp-image-19200\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/insulin-and-hepcidin-are-co-secreted-fb.png\" alt=\"hepcidin and insulin are besties\" width=\"401\" height=\"529\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/insulin-and-hepcidin-are-co-secreted-fb.png 401w, https://betterbodychemistry.com/wp-content/uploads/2019/02/insulin-and-hepcidin-are-co-secreted-fb-227x300.png 227w\" sizes=\"(max-width: 401px) 100vw, 401px\" />You’ve got iron issues……….</p>\n<p>It’s a bit of a surprise, your diet is NOT perfect, but you do eat iron containing foods, such as meat. And you start your morning with a bowl of cereal, which according to the box, has 9 vitamins and minerals, including iron.</p>\n<p>So what gives ?</p>\n<h3 style=\"text-align: center;\">Well the biology of iron is complicated.</h3>\n<p>First thing to know, is iron is a grocery……</p>\n<h2><span style=\"color: #f21f02;\"><strong>Iron is precious</strong></span></h2>\n<p>A rather precious one.</p>\n<h3 style=\"text-align: center;\">What makes it precious, is it’s relative scarcity.</h3>\n<p>But, the operative word, is relative. You do need to get a little bit of iron, from your food, primarily to top up, the little bit of iron, you lose, on a daily basis.</p>\n<p style=\"text-align: left;\"><em>NOTE : A big bleed and having a baby, can up the need.</em></p>\n<h3 style=\"text-align: center;\">But the bulk of your iron needs, are met, by iron recycling.</h3>\n<p><img class=\"aligncenter size-full wp-image-19196\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/iron-requirement.png\" alt=\"the iron cycle in humans\" width=\"500\" height=\"459\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/iron-requirement.png 500w, https://betterbodychemistry.com/wp-content/uploads/2019/02/iron-requirement-300x275.png 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" /></p>\n<p>So there is more to the iron story, than iron absorption, because………..</p>\n<h2><span style=\"color: #f21f02;\"><strong>Iron is precocious</strong></span></h2>\n<p><img class=\"alignright size-full wp-image-19197\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/insulin-puts-away-iron.png\" alt=\"insulin puts away iron\" width=\"302\" height=\"271\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/insulin-puts-away-iron.png 302w, https://betterbodychemistry.com/wp-content/uploads/2019/02/insulin-puts-away-iron-300x269.png 300w\" sizes=\"(max-width: 302px) 100vw, 302px\" />Too much iron in the blood, at any given point in time, is problematic.</p>\n<h3 style=\"text-align: center;\">The risk is part microbial, part metabolic.</h3>\n<p>So it is important, to put any iron arriving, away quickly and efficiently. The guy in charge of putting away the groceries, is insulin.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Insulin and iron</strong></span></h2>\n<p>Now most of the time, when we talk about insulin’s exploits, we think glucose.</p>\n<p>This is the job, insulin “fluff’sâ€� up……….</p>\n<h3 style=\"text-align: center;\">Leading to glucose spikes and other metabolic troubles.</h3>\n<p>But insulin is also involved in preventing iron spikes.  This is what a group of researchers from Austria recently uncovered.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Looking for iron</strong></span></h2>\n<p>They asked healthy adults to do a glucose tolerance test – which amounts to downing a syrupy liquid, chock full of glucose, and then watching what happens, to sugar levels. Now what made their study, interesting, was in addition to keeping tabs on the usual sugar related parameters, they also kept tabs, on a couple of iron related parameters.</p>\n<p>Here is what happened….</p>\n<div id=\"attachment_19198\" style=\"width: 640px\" class=\"wp-caption aligncenter\"><img class=\"size-full wp-image-19198\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/graph-showing-iron-levels-in-response-to-glucose-intake.png\" alt=\"graph showing iron levels in response to glucose uptake\" width=\"630\" height=\"604\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/graph-showing-iron-levels-in-response-to-glucose-intake.png 630w, https://betterbodychemistry.com/wp-content/uploads/2019/02/graph-showing-iron-levels-in-response-to-glucose-intake-300x288.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/02/graph-showing-iron-levels-in-response-to-glucose-intake-300x288@2x.png 600w\" sizes=\"(max-width: 630px) 100vw, 630px\" /><p class=\"wp-caption-text\">Changes of serum glucose, C-peptide, iron and hepcidin concentrations in response to oral administration of 75 g glucose (red) or water (black). Copyright 2013 Elsevier Inc</p></div>\n<p>Downing the sugar, caused a spike in glucose and “insulinâ€�. At the same time, sugar levels were rising, iron levels took a dive.</p>\n<p>The driver for this decline, was hepcidin – it’s levels tracked the rise in glucose and “insulinâ€�.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Beta cells pump out hepcidin</strong></span></h2>\n<p>When the team probed a little further, they found that the hepcidin, doing the WORK, was not coming from the liver, it was coming from the pancreas.</p>\n<h3 style=\"text-align: center;\">And it was related to the amount of glucose.</h3>\n<p><img class=\"aligncenter size-full wp-image-19199\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/insulin-and-hepcidin-are-co-secreted.png\" alt=\"insulin and hepcidin being co-secreted by beta cell\" width=\"504\" height=\"382\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/insulin-and-hepcidin-are-co-secreted.png 504w, https://betterbodychemistry.com/wp-content/uploads/2019/02/insulin-and-hepcidin-are-co-secreted-300x227.png 300w\" sizes=\"(max-width: 504px) 100vw, 504px\" /></p>\n<p>The team concluded, when the pancreas spits out insulin, hepcidin comes along for the ride i.e. the two hormones are co-secreted.</p>\n<h2><span style=\"color: #f21f02;\"><strong>The hepcidin-iron-insulin connection</strong></span></h2>\n<p>Insulin doesn’t actually touch iron. Hepcidin handles the iron side of things – IN THE MOMENT !</p>\n<p>It’s a smart move…….</p>\n<p><strong> </strong>After all, a bite of something, could bring a rush of iron, into the system, resulting in an iron spike, thanks to a momentary shortage of iron transporters / chaperones.</p>\n<h3 style=\"text-align: center;\">Now an iron spike, could tip the balance, leading to a SERIOUS problem.</h3>\n<p>The blast of hepcidin, tells “everyoneâ€� to HOLD ONTO their iron resources, until the situation returns to normal.</p>\n<p>Well this is what should happen…………..</p>\n<h2><span style=\"color: #f21f02;\"><strong>Hepcidin never stands down</strong></span></h2>\n<p>Because insulin secretion, never ceases……</p>\n<p style=\"text-align: center;\"><em>Remember when the pancreas spits out insulin, hepcidin comes along for the ride.</em></p>\n<p>When hepcidin levels are high, morning, noon and night, this makes moving iron around the body,  A LITTLE DIFFICULT. If the situation becomes bad enough, you can develop signs and symptoms of iron deficiency.</p>\n<p>It could show up, as overt anamia or in other ways, e.g. early grey hair and restless leg syndrome.</p>\n<h2><span style=\"color: #f21f02;\"><strong>To “fixâ€� the iron “deficiencyâ€�</strong></span></h2>\n<p>You don’t NEED MORE IRON !  You need, the iron you’ve got, to be recycled.</p>\n<p><img class=\"aligncenter size-full wp-image-19201\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/liver-blaming-hepcidin-for-being-overburdened-with-iron.png\" alt=\"liver blaming hepcidin for being overburdened with iron\" width=\"467\" height=\"261\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/liver-blaming-hepcidin-for-being-overburdened-with-iron.png 467w, https://betterbodychemistry.com/wp-content/uploads/2019/02/liver-blaming-hepcidin-for-being-overburdened-with-iron-300x168.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/02/liver-blaming-hepcidin-for-being-overburdened-with-iron-320x180.png 320w\" sizes=\"(max-width: 467px) 100vw, 467px\" /></p>\n<h2 style=\"text-align: center;\">To do this, you need to rein in hepcidin.</h2>\n<h1 style=\"text-align: center;\">The way rein in hepcidin, is to rein in insulin.</h1>\n<h2><span style=\"color: #f21f02;\"><strong>The biology of hepcidin</strong></span></h2>\n<p>Hepcidin and insulin are NOT “joinedâ€� at the hip, several other things contribute to your hepcidin levels and iron status, but since insulin and hepcidin, are BIG BUDDIES.</p>\n<h2 style=\"text-align: center;\">If you’re insulin resistant, this is the place to start.</h2>\n<p>Download our free <a href=\"http://www.betterbodychemistry.com/willpower-report/\">Willpower repor</a>t, to discover 10 strategies you can use, to REIN IN INSULIN, and HEPCIDIN.</p>\n<p>PS. If you want to learn more about hepcidin’s role  in insulin resistance, watch the <a href=\"https://betterbodychemistry.com/ir/hepcidin-insulin-resistance/\">hepcidin video</a> in our special <a href=\"https://betterbodychemistry.com/insulin-resistance-system/\">“Ups and Downs of insulin resistance” series.</a></p>\n<p><br />\n<div class=\"symple-box yellow none \" style=\"text-align:left; width:100%;\"> <a href=\"http://dx.doi.org/10.1016/j.jnutbio.2012.02.017\"><strong>Glucose acts as a regulator of serum iron by increasing serum hepcidin concentrations.</strong></a> Journal of Nutritional Biochemistry 24 (2013) 112–117.Elmar Aignera, Thomas K. Feldera, Hannes Oberkoflera, Penelope Hahnea, Simon Auera, Selma Soyala, Andreas Stadlmayrb, Karin Schwenohab, Christian Pirichc, Paul Hengsterd, Christian Datzb, Wolfgang Patsch</div>\n<h2>Further reading</h2>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-11523\" src=\"https://betterbodychemistry.com/wp-content/uploads/2013/02/estrogen-being-ordered-out-during-a-hysterectomy-tn.png\" alt=\"estrogen being ordered out during a hysterectomy\" width=\"125\" height=\"125\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/aging/brain-iron-causes-rust/\">If you want to stop brain rust – install a red robot</a></p>\n<p>Iron accumulates inside the human body, especially the brain. Iron and oxygen don’t mix……. the combination leads to rusty parts and serious breakdowns.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-11521\" src=\"https://betterbodychemistry.com/wp-content/uploads/2013/02/iron-causing-the-pancreas-to-rust-tn.png\" alt=\"iron causing the pancreas to rust\" width=\"125\" height=\"125\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/diabetes/iron-pump-diabetes/\">Turning down an iron pump – irons out diabetes</a></p>\n<p>When an iron pump in the pancreas runs full steam for too long, beta cells die and diabetes begins. Turning the pump down, is enough to stop diabetes.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-last symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-11396\" src=\"https://betterbodychemistry.com/wp-content/uploads/2013/02/vampire-dracula-fixing-metabolic-syndrome-tn.png\" alt=\"vampire dracula fixing metabolic syndrome\" width=\"125\" height=\"125\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/heart-disease/high-blood-pressure-vampire/\">Suffering from high blood pressure – you need a vampire ?</a></p>\n<p>If you’re suffering from metabolic syndrome – maybe it is time to let the iron out and bring down your blood pressure by giving a little blood.</p>\n</div>\n<p> </p>\n<h2 style=\"text-align: center;\"><span style=\"color: #c33035;\">Want to discover more ways to create BETTER BODY CHEMISTRY ?</span></h2>\n<div class=\'_form_1213\'></div><script type=\'text/javascript\' src=\'https://spoonfulofscience.activehosted.com/f/embed.php?id=1213&5C9179B1D6093&nostyles=1\'></script>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/obesity/iron-deficiency-insulin/\">When your iron deficiency is NOT an iron deficiency</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:36:\"http://wellformedweb.org/CommentAPI/\";a:1:{s:10:\"commentRss\";a:1:{i:0;a:5:{s:4:\"data\";s:69:\"https://betterbodychemistry.com/obesity/iron-deficiency-insulin/feed/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:38:\"http://purl.org/rss/1.0/modules/slash/\";a:1:{s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:1:\"0\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}}}i:5;a:6:{s:4:\"data\";s:66:\"\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n \n \n \n \n \n \";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";s:5:\"child\";a:5:{s:0:\"\";a:7:{s:5:\"title\";a:1:{i:0;a:5:{s:4:\"data\";s:57:\"When to take an aspirin to lower your cardiovascular risk\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"link\";a:1:{i:0;a:5:{s:4:\"data\";s:67:\"https://betterbodychemistry.com/heart-disease/when-to-take-aspirin/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:75:\"https://betterbodychemistry.com/heart-disease/when-to-take-aspirin/#respond\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:7:\"pubDate\";a:1:{i:0;a:5:{s:4:\"data\";s:31:\"Thu, 07 Feb 2019 07:00:04 +0000\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"category\";a:9:{i:0;a:5:{s:4:\"data\";s:13:\"Heart disease\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:1;a:5:{s:4:\"data\";s:7:\"aspirin\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:2;a:5:{s:4:\"data\";s:13:\"chronotherapy\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:3;a:5:{s:4:\"data\";s:5:\"clots\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:4;a:5:{s:4:\"data\";s:11:\"eicosanoids\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:5;a:5:{s:4:\"data\";s:12:\"heart attack\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:6;a:5:{s:4:\"data\";s:9:\"platelets\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:7;a:5:{s:4:\"data\";s:11:\"thromboxane\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:8;a:5:{s:4:\"data\";s:21:\"women’s health\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"guid\";a:1:{i:0;a:5:{s:4:\"data\";s:40:\"https://betterbodychemistry.com/?p=19033\";s:7:\"attribs\";a:1:{s:0:\"\";a:1:{s:11:\"isPermaLink\";s:5:\"false\";}}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:11:\"description\";a:1:{i:0;a:5:{s:4:\"data\";s:418:\"<p>The time of the day, you want to stop platelet MOBBING is FIRST THING IN THE MORNING. To do this, you should be taking aspirin with dinner, NOT breakfast.</p>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/heart-disease/when-to-take-aspirin/\">When to take an aspirin to lower your cardiovascular risk</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:32:\"http://purl.org/dc/elements/1.1/\";a:1:{s:7:\"creator\";a:1:{i:0;a:5:{s:4:\"data\";s:8:\"Dr Sandy\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:40:\"http://purl.org/rss/1.0/modules/content/\";a:1:{s:7:\"encoded\";a:1:{i:0;a:5:{s:4:\"data\";s:15494:\"<p><iframe src=\"https://www.youtube.com/embed/Ehv32sffuRU\" width=\"640\" height=\"480\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"></iframe></p>\n\n<p>Click to listen to the audio…<br />\n<script type=\"text/javascript\" src=\"//spoonfulofscience.audello.com/player/dXNpbmctYXNwaXJpbmctdG8tcHJldmVudC1hLWhlYXJ0LWF0dGFjay1nZXQtdGhlLXQubXAz/?container=audello-0SIBWB5WWV\" async></script></p>\n<div id=\"audello-0SIBWB5WWV\" class=\"audello-player audello-file\" data-role=\"audello-file\" data-audello-id=\"dXNpbmctYXNwaXJpbmctdG8tcHJldmVudC1hLWhlYXJ0LWF0dGFjay1nZXQtdGhlLXQubXAz\"></div>\n<h2 style=\"text-align: left;\">The best time to take an aspirin, to lower the risk of having a heart attack</h2>\n<div id=\"attachment_19163\" style=\"width: 411px\" class=\"wp-caption alignright\"><img class=\"size-full wp-image-19163\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/aspirin-at-night-stops-blood-clots.png\" alt=\"aspirin at night stops blood clotting\" width=\"401\" height=\"455\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/aspirin-at-night-stops-blood-clots.png 401w, https://betterbodychemistry.com/wp-content/uploads/2019/02/aspirin-at-night-stops-blood-clots-264x300.png 264w\" sizes=\"(max-width: 401px) 100vw, 401px\" /><p class=\"wp-caption-text\">The time of the day, you want to stop platelet MOBBING is FIRST THING IN THE MORNING. To do this, you should be taking aspirin with dinner, NOT breakfast.</p></div>\n<p>You’re worried about dying of a heart attack.</p>\n<p>Maybe your doctor is worried about this too and has prescribed a daily baby aspirin, as a PRECAUTION. The biology behind the PRECAUTION, stems from the fact that taking aspirin, takes away the ability of  platelets, t<a href=\"http://betterbodychemistry.com/aspirin-salicylic-acid/cardiovascular-power-pain-killer-aspirin-unplugged/\">o produce thromboxane.</a></p>\n<h3 style=\"text-align: center;\">With no thromboxane, the platelet is anti-social.</h3>\n<p>It won’t get together with friends…………</p>\n<h2><span style=\"color: #f21f02;\"><strong>A mob of platelets</strong></span></h2>\n<p>Since you need a mob of platelets, to form a clot, block blood vessels, the risk of a block in a blood vessel, is significantly lower, when taking aspirin.</p>\n<p style=\"text-align: center;\">Now blocks in blood vessels are NOT all bad !</p>\n<p style=\"text-align: center;\">Should there be a pipe burst or rupture, those blocks become life saving.</p>\n<p>But, when they happen in “the wrongâ€� place,  which is usually brought on by a case of bad body chemistry, the block can be tickets, because….</p>\n<h2><span style=\"color: #f21f02;\"><strong>Starved of oxygen</strong></span></h2>\n<p>The cells in the vicinity of the block, find themselves WITHOUT OXYGEN.</p>\n<h3 style=\"text-align: center;\">And oxygen IS A REQUIREMENT, for life.</h3>\n<p>This applies to individual cells and you the whole person.</p>\n<h2><span style=\"color: #f21f02;\"><strong>It’s a fine balance</strong></span></h2>\n<p>Now rendering  your platelets in-operable, does have some risk, but  sometimes the benefits, outweigh the risks.</p>\n<p><em>NOTE : This really is something you should discuss with your doctor. Just because you can buy aspirin at the local supermarket, does not mean a baby aspirin a day, is the “rightâ€� strategy for you. </em></p>\n<p>But when it is……………</p>\n<h3 style=\"text-align: center;\">You want to maximize the aspirin benefit.</h3>\n<p>And to do this, it helps to understand the biology.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Platelets are LARKS</strong></span></h2>\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-19164\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/platelet-chronotype.png\" alt=\"platelet chronotype\" width=\"626\" height=\"355\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/platelet-chronotype.png 626w, https://betterbodychemistry.com/wp-content/uploads/2019/02/platelet-chronotype-300x170.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/02/platelet-chronotype-320x180.png 320w, https://betterbodychemistry.com/wp-content/uploads/2019/02/platelet-chronotype-300x170@2x.png 600w\" sizes=\"(max-width: 626px) 100vw, 626px\" /></p>\n<p style=\"text-align: center;\">Seriously…………. these little guys, typically MOB early in the morning.</p>\n<p>We know this, because more cardiovascular events happen between 6 am and noon. And morning events, tend to be more damaging, than events that happen later in the day.</p>\n<p>So the time of the day, you want to stop platelet MOBBING is ……….</p>\n<h3 style=\"text-align: center;\">FIRST THING IN THE MORNING.</h3>\n<h2><span style=\"color: #f21f02;\"><strong>Start you day with an aspirin</strong></span></h2>\n<p>Well this is the recommendation, but, biology is complicated………..</p>\n<h3 style=\"text-align: center;\">The problem, aspirin doesn’t work, 24/7.</h3>\n<p>You see, when you swallow the pill, with breakfast, the aspirin gets to work quickly.</p>\n<p><em>NOTE : And you should swallow your aspirin pill with some food………….. an unaccompanied aspirin, can burn a hole in your gut lining.</em></p>\n<h2><span style=\"color: #f21f02;\"><strong>It turns platelets anti-social</strong></span></h2>\n<p>INSTANTLY.</p>\n<p><img class=\"aligncenter size-full wp-image-19166\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/meet-and-tweet.png\" alt=\"platelet tweet party\" width=\"424\" height=\"369\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/meet-and-tweet.png 424w, https://betterbodychemistry.com/wp-content/uploads/2019/02/meet-and-tweet-300x261.png 300w\" sizes=\"(max-width: 424px) 100vw, 424px\" /></p>\n<p style=\"text-align: center;\">90 % of the platelets, present in the blood, when the aspirin arrives, are impacted.</p>\n<p>But the aspirin doesn’t stick around for long. In the average person, most of the aspirin will be gone by dinner time.</p>\n<h3 style=\"text-align: center;\">And by dinner time, there’ll be new platelet arrivals.</h3>\n<p><a href=\"baby platelets\"><img class=\"aligncenter size-full wp-image-19167\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/baby-platlets.png\" alt=\"g\" width=\"613\" height=\"446\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/baby-platlets.png 613w, https://betterbodychemistry.com/wp-content/uploads/2019/02/baby-platlets-300x218.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/02/baby-platlets-300x218@2x.png 600w\" sizes=\"(max-width: 613px) 100vw, 613px\" /></a></p>\n<p>Exactly how many, will depend on your body chemistry. Unfortunately, if your body chemistry is NOT GOOD, there’ll be quite a lot more……….</p>\n<p>Remember, platelets are LIFE SAVING !</p>\n<h2><span style=\"color: #f21f02;\"><strong>Late in the evening</strong></span></h2>\n<p>The swell in brand new rearing to go platelets, means there are now more platelets available, for a platelet GET-TOGETHER. And since you’re NOT MOVING, all that much at 3 am in the morning, the possibility of a stick up, rises, significantly.</p>\n<p><img class=\"aligncenter size-full wp-image-19168\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/platelets-playing-twister.png\" alt=\"platelets playing twister i.e. clotting\" width=\"480\" height=\"270\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/platelets-playing-twister.png 480w, https://betterbodychemistry.com/wp-content/uploads/2019/02/platelets-playing-twister-300x169.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/02/platelets-playing-twister-320x180.png 320w\" sizes=\"(max-width: 480px) 100vw, 480px\" /></p>\n<p style=\"text-align: center;\">And with it…………… the risk of a cardiovascular event. Eish !</p>\n<p>So can we time things differently ?</p>\n<p>This is what a team of Polish researchers wondered – would taking aspirin in the evening, be better ?</p>\n<h2><span style=\"color: #f21f02;\"><strong>Morning versus evening aspirin</strong></span></h2>\n<p>They tested out their theory in people, who were taking an aspirin a day, because they had been diagnosed with CAD i.e. they were at a high risk of suffering a cardiovascular event.</p>\n<p style=\"text-align: center;\">The ability of these people’s platelets to aggregate in the lab was measured.</p>\n<p>Here are the results…</p>\n<div id=\"attachment_19169\" style=\"width: 555px\" class=\"wp-caption aligncenter\"><img class=\"size-full wp-image-19169\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/how-aspirin-impacts-platelet-clotting-in-vitro.png\" alt=\"platelets clotting in lab \" width=\"545\" height=\"341\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/how-aspirin-impacts-platelet-clotting-in-vitro.png 545w, https://betterbodychemistry.com/wp-content/uploads/2019/02/how-aspirin-impacts-platelet-clotting-in-vitro-300x188.png 300w\" sizes=\"(max-width: 545px) 100vw, 545px\" /><p class=\"wp-caption-text\">Change in Aspirin Reaction Units (ARU) following 3 months of taking aspirin at different times of the day.  <em>Copyright 2019 Via Medica</em></p></div>\n<p>Taking aspirin really does lower the ability of the platelets to aggregate, no matter what time of the day, you take it.</p>\n<h3 style=\"text-align: center;\">But to maximize the effect, it is better to take it in the evening.</h3>\n<p>Especially if you are a lady….</p>\n<h2><strong>Aspirin therapy for women</strong></h2>\n<p>When the researchers analysed their results, according to gender, they found, morning aspirin, actually made things “worseâ€� for ladies, not “betterâ€�.</p>\n<div id=\"attachment_19170\" style=\"width: 582px\" class=\"wp-caption aligncenter\"><img class=\"size-full wp-image-19170\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/morning-aspirin-in-women.png\" alt=\"effect of aspirin timing in women\" width=\"572\" height=\"374\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/02/morning-aspirin-in-women.png 572w, https://betterbodychemistry.com/wp-content/uploads/2019/02/morning-aspirin-in-women-300x196.png 300w\" sizes=\"(max-width: 572px) 100vw, 572px\" /><p class=\"wp-caption-text\">Change in Aspirin Reaction Units (ARU) in men versus women. <em>Copyright 2019 Via Medica</em></p></div>\n<p style=\"text-align: center;\"><strong> </strong>Now this is not actually a big surprise.</p>\n<p>Numerous studies have hinted that taking aspirin, <a href=\"http://betterbodychemistry.com/aspirin-salicylic-acid/aspirin-discriminates-women/\">is not all that helpful for women</a>…..this because the biology of heart disease in men and women, is different.</p>\n<h2><span style=\"color: #f21f02;\"><strong>When you take your aspirin </strong></span></h2>\n<p>Matters…..</p>\n<p>If you’ taking an aspirin a day, to lower your risk of a cardiovascular event, then it might be prudent to take your pill, with dinner.</p>\n<p>Especially if you’re a lady !</p>\n<p><em>NOTE : Not all cardiovascular events are a result of BLOCKS, some are BLEEDS. Opting to take an aspirin prophylactically is a “bigâ€� decision, discuss it with your physician. </em></p>\n\n<div class=\"symple-box yellow none \" style=\"text-align:left; width:100%;\"> <a href=\"http://10.5603/CJ.a2018.0142/\"><strong>The effect of acetylsalicylic acid dosed at bedtime on the antiaggregation effect in patients with coronary heart disease and arterial hypertension: A randomized, controlled trial.</strong></a> Cardiology Journal (2018) . Beata Krasi?ska, Lech Paluszkiewicz, Ewa Miciak-Lawicka, Maciej Krasi?ski, Piotr Rzymski, Andrzej Tykarski, Zbigniew Krasi?ski</div>\n<h2>Further reading</h2>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-14586\" src=\"https://betterbodychemistry.com/wp-content/uploads/2015/07/heart-keeping-time-tn1.png\" alt=\"heart keeping time\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2015/07/heart-keeping-time-tn1.png 125w, https://betterbodychemistry.com/wp-content/uploads/2015/07/heart-keeping-time-tn1-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2015/07/heart-keeping-time-tn1-55x55.png 55w, https://betterbodychemistry.com/wp-content/uploads/2015/07/heart-keeping-time-tn1-55x55@2x.png 110w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"https://www.betterbodychemistry.com/heart-disease/asleep-blood-pressure/\">Dipping into high blood pressure – are you solving the problem ?</a></p>\n<p>The time you want your blood pressure to be LOW, is not when you’ve visiting your doctor, you need it to be low, when you’re SLEEPING. What is your asleep BP ?</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-4257\" src=\"https://betterbodychemistry.com/wp-content/uploads/2011/08/cells-lining-stomach-being-burnt-because-of-aspirin-tn.png\" alt=\"cells lining stomach being burnt because of aspirin\" width=\"125\" height=\"124\" /></p>\n<p><a href=\"http://betterbodychemistry.com/aspirin-salicylic-acid/watch-aspirin-burns-holes-stomach/\">Watch out, aspirin burns holes in your stomach</a></p>\n<p>Some people feel the burn when they take an aspirin, but even tough guys are being burned by the pill. Aspirin can’t help it, that is how it works.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-last symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-14754\" src=\"https://betterbodychemistry.com/wp-content/uploads/2015/09/sugar-stripping-the-glycocalyx-lining-the-blood-vessel-tn.png\" alt=\"sugar stripping the glycoccalyx\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2015/09/sugar-stripping-the-glycocalyx-lining-the-blood-vessel-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2015/09/sugar-stripping-the-glycocalyx-lining-the-blood-vessel-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2015/09/sugar-stripping-the-glycocalyx-lining-the-blood-vessel-tn-55x55.png 55w, https://betterbodychemistry.com/wp-content/uploads/2015/09/sugar-stripping-the-glycocalyx-lining-the-blood-vessel-tn-55x55@2x.png 110w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/obesity/blood-vessels-clog-sticky/\">Blood vessels clog up when they become sticky</a></p>\n<p>A special non-stick layer, known as the glycocalyx, prevents things from sticking to the sides of blood vessels. When it’s not there, atherosclerosis happens.</p>\n</div>\n<h2><span style=\"color: #c33035;\">Want to discover more ways to create BETTER BODY CHEMISTRY ?</span></h2>\n<div class=\'_form_1213\'></div><script type=\'text/javascript\' src=\'https://spoonfulofscience.activehosted.com/f/embed.php?id=1213&5C9179B1DB5D7&nostyles=1\'></script>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/heart-disease/when-to-take-aspirin/\">When to take an aspirin to lower your cardiovascular risk</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:36:\"http://wellformedweb.org/CommentAPI/\";a:1:{s:10:\"commentRss\";a:1:{i:0;a:5:{s:4:\"data\";s:72:\"https://betterbodychemistry.com/heart-disease/when-to-take-aspirin/feed/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:38:\"http://purl.org/rss/1.0/modules/slash/\";a:1:{s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:1:\"0\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}}}i:6;a:6:{s:4:\"data\";s:72:\"\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n \n \n \n \n \n \";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";s:5:\"child\";a:5:{s:0:\"\";a:7:{s:5:\"title\";a:1:{i:0;a:5:{s:4:\"data\";s:30:\"Hepcidin in insulin resistance\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"link\";a:1:{i:0;a:5:{s:4:\"data\";s:63:\"https://betterbodychemistry.com/ir/hepcidin-insulin-resistance/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:71:\"https://betterbodychemistry.com/ir/hepcidin-insulin-resistance/#respond\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:7:\"pubDate\";a:1:{i:0;a:5:{s:4:\"data\";s:31:\"Thu, 31 Jan 2019 07:33:35 +0000\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"category\";a:11:{i:0;a:5:{s:4:\"data\";s:2:\"IR\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:1;a:5:{s:4:\"data\";s:7:\"anaemia\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:2;a:5:{s:4:\"data\";s:6:\"anemia\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:3;a:5:{s:4:\"data\";s:11:\"enterocytes\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:4;a:5:{s:4:\"data\";s:11:\"ferriportin\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:5;a:5:{s:4:\"data\";s:8:\"hepcidin\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:6;a:5:{s:4:\"data\";s:18:\"insulin resistance\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:7;a:5:{s:4:\"data\";s:4:\"iron\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:8;a:5:{s:4:\"data\";s:15:\"iron deficiency\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:9;a:5:{s:4:\"data\";s:11:\"macrophages\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:10;a:5:{s:4:\"data\";s:15:\"red blood cells\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"guid\";a:1:{i:0;a:5:{s:4:\"data\";s:40:\"https://betterbodychemistry.com/?p=19145\";s:7:\"attribs\";a:1:{s:0:\"\";a:1:{s:11:\"isPermaLink\";s:5:\"false\";}}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:11:\"description\";a:1:{i:0;a:5:{s:4:\"data\";s:375:\"<p>We look at hepcidin, the body\'s iron king pin. Thanks to his antics, if you\'re insulin resistant, you\'re short of iron, while wallowing in it.</p>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/ir/hepcidin-insulin-resistance/\">Hepcidin in insulin resistance</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:32:\"http://purl.org/dc/elements/1.1/\";a:1:{s:7:\"creator\";a:1:{i:0;a:5:{s:4:\"data\";s:8:\"Dr Sandy\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:40:\"http://purl.org/rss/1.0/modules/content/\";a:1:{s:7:\"encoded\";a:1:{i:0;a:5:{s:4:\"data\";s:16214:\"<p><iframe src=\"https://www.youtube.com/embed/_FZlksBKooY\" width=\"640\" height=\"480\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"></iframe></p>\n\n<p>Click to listen to the audio…<br />\n<script type=\"text/javascript\" src=\"//spoonfulofscience.audello.com/player/aGVwY2lkaW4taW4taW5zdWxpbi1yZXNpc3RhbmNlLm1wMw==/?container=audello-W1WFZND2OZ\" async></script></p>\n<div id=\"audello-W1WFZND2OZ\" class=\"audello-player audello-file\" data-role=\"audello-file\" data-audello-id=\"aGVwY2lkaW4taW4taW5zdWxpbi1yZXNpc3RhbmNlLm1wMw==\"></div>\n<p><a href=\"https://prezi.com/p/tnco1ragklpb/\">Click here</a> to view the prezi.</p>\n<p>When you’re insulin resistant, that is, you’ve got  metabolic syndrome, pretty much every chemical in the body is NOT QUITE RIGHT. Some are up. Some are down. Few are actually at physiologically NORMAL levels.</p>\n<p>Traditionally the focus is on the big guns.</p>\n<ul>\n<li>Sugar</li>\n<li>Insulin</li>\n<li>And cholesterol</li>\n</ul>\n<p>In this series, we  take a look at some of the other players.</p>\n<p>Who they are, what they’re up to and how they’re part of the state of insulin resistance.</p>\n<p>This week, we’re not actually looking at a chemical <em>per se</em>, instead we take a look at the behaviour of tiny little pressure receptors, called baroreceptors, which are embedded in the blood vessels, that leave the heart.</p>\n<h1 style=\"text-align: center;\"><strong>Hepcidin in the insulin resistant</strong></h1>\n<p>Now, hepcidin is UP and this impacts iron metabolism –  typically manifesting an “apparentâ€� iron deficiency.</p>\n<p>So who is hepcidin ?</p>\n<h2><span style=\"color: #f21f02;\"><strong>The mining magnet</strong></span></h2>\n<p>Well is a mining magnet, controlling the acquisition, storage and utilization of iron in the body.</p>\n<p style=\"text-align: center;\">He controls EVERY cell’s access to IRON, either directly or indirectly.</p>\n<p>And EVERY CELL,   includes all the cells that make up the human body, from your brain to your big toe, as well as any microbial cells, keen to take up residence.</p>\n<p>In the body, iron is a precious commodity, it runs a lot of chemistry……..</p>\n<h2><span style=\"color: #f21f02;\"><strong>The chemistry of iron</strong></span></h2>\n<p>The chemistry that springs to mind, for most people is oxygen delivery.  Iron is the molecule at the centre of haemoglobin, which is the protein responsible for carrying and delivering oxygen.</p>\n<h3 style=\"text-align: center;\">And oxygen is a REQUIREMENT for life.</h3>\n<p><img class=\"aligncenter size-full wp-image-19147\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/oxygen-delivery.png\" alt=\"oxygen delivery\" width=\"607\" height=\"331\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/oxygen-delivery.png 607w, https://betterbodychemistry.com/wp-content/uploads/2019/01/oxygen-delivery-300x164.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/01/oxygen-delivery-300x164@2x.png 600w\" sizes=\"(max-width: 607px) 100vw, 607px\" /></p>\n<p>But, iron is involved in respiration, DNA synthesis, detoxification, regulation of gene expression, as well as growth and development. Overt shortages of iron, typically show up, as anaemia.</p>\n<p>Anaemia is not ALWAYS about iron……………but 9 times out of 10, it is.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Hepcidin is a shrewd business man</strong></span></h2>\n<p>When you run a mining operation, is not the same, as running a bank, you’ve got to be tough and hands on. Hepcidin, uses brute force, to run the mining operation.  His modus operandi, is to control the one and only, iron exporter pump.</p>\n<h2 style=\"text-align: center;\">Hepcidin, renders this pump, inoperable.</h2>\n<p>In one foul swoop, hepcidin controls the entire iron supply chain…..</p>\n<h2><span style=\"color: #f21f02;\"><strong>Ferroportin pumps</strong></span></h2>\n<p>Are located in several types of cells, notably</p>\n<ul>\n<li>Enterocytes, which are the cells that line the gut and</li>\n<li>Marcophages, the workhorses of the immune system</li>\n</ul>\n<p>The enterocytes are responsible for iron uptake, while the macrophages control iron distrubtion.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Iron uptake takes a knock</strong></span></h2>\n<p>Disabling ferriportin in the enterocytes, stops mining operations.</p>\n<p>It all starts with dietary iron, which maybe bountiful or rather iron deficient.   Either way, the enterocytes grab as many iron molecules, as  they can, when they pass their way.    The iron that is gathered is then moved inside for storage. From here it is moved into the body, by the ferriportin pump.</p>\n<p><img class=\"aligncenter size-full wp-image-19148\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/enterocytes-1.png\" alt=\"ferriportin on enterocytes\" width=\"591\" height=\"339\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/enterocytes-1.png 591w, https://betterbodychemistry.com/wp-content/uploads/2019/01/enterocytes-1-300x172.png 300w\" sizes=\"(max-width: 591px) 100vw, 591px\" /></p>\n<h2 style=\"text-align: center;\">Assuming the pump is operational.</h2>\n<p><img class=\"aligncenter size-full wp-image-19149\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/no-iron-entering-the-circulation.png\" alt=\"no iron entering circulation\" width=\"420\" height=\"266\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/no-iron-entering-the-circulation.png 420w, https://betterbodychemistry.com/wp-content/uploads/2019/01/no-iron-entering-the-circulation-300x190.png 300w\" sizes=\"(max-width: 420px) 100vw, 420px\" /></p>\n<p>If not, well the iron is stored, until it can be moved out or the enterocyte falls into the abyss – which ever comes first.</p>\n<p><em>NOTE : Enterocytes days are numbered, they live for 3 – 5 days.  They’re born in the villi crypts and then move up, to the top of the villi, where they get sloughed off.  When this happens, they take their iron supply with them.  </em></p>\n<p>So iron uptake takes a knock……</p>\n<h2><span style=\"color: #f21f02;\"><strong>Iron distribution is ALSO curtailed</strong></span></h2>\n<p>Macrophages come in different shapes, the one’s stationed in the spleen are professional, iron guzzlers.</p>\n<p>Old, damaged red blood cells, are euthanized in the spleen. It’s a controlled process, very civilized, the macrophages in the red pulp, gather all the iron, the red blood cell is carrying.</p>\n<h2 style=\"text-align: center;\">And for the record, it’s A LOT.</h2>\n<p><img class=\"aligncenter size-full wp-image-19150\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/rbc-hb.png\" alt=\"the iron in a red blood cell\" width=\"595\" height=\"318\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/rbc-hb.png 595w, https://betterbodychemistry.com/wp-content/uploads/2019/01/rbc-hb-300x160.png 300w\" sizes=\"(max-width: 595px) 100vw, 595px\" /></p>\n<p>An average red blood cell has 280 million molecules of haemoglobin. And one haemoblogin has 4 heme groups and there is a iron molecule, buried in the centre of each heme group. So we’re talking about over 1 billion iron atoms per red blood cell. And millions of red blood cells are being “euthanized’ per minute.</p>\n<h3 style=\"text-align: center;\">The macrophages gather it all up and make it available for recycling.</h3>\n<p>Assuming the ferriportin pump is functioning. When it’s not, they hold onto it – this leads to systemic shortages.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Keeping iron levels in check </strong></span></h2>\n<p>Now you might be thinking, why would hepcidin deliberately keep iron levels low ?</p>\n<h3 style=\"text-align: center;\">Iron is a good thing !</h3>\n<h2 style=\"text-align: center;\">But too much of a good thing is a bad thing.</h2>\n<p>This is particularly true, when there is a possibility of a microbial invasion. To go forth and multiply, bacteria need iron.  They will beg, borrow or steal it.</p>\n<h3 style=\"text-align: center;\">Hepcidin KNOWS this, so he deliberately keeps iron out of their reach.</h3>\n<p><img class=\"aligncenter size-full wp-image-19152\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/supply-and-deman.png\" alt=\"iron supply versus demand\" width=\"608\" height=\"340\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/supply-and-deman.png 608w, https://betterbodychemistry.com/wp-content/uploads/2019/01/supply-and-deman-300x168.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/01/supply-and-deman-320x180.png 320w, https://betterbodychemistry.com/wp-content/uploads/2019/01/supply-and-deman-300x168@2x.png 600w\" sizes=\"(max-width: 608px) 100vw, 608px\" /></p>\n<p>Which is why hepcidin levels are typically high during an infection or if there is inflammation.</p>\n<p>But, it is a fine balance…..</p>\n<h2><span style=\"color: #f21f02;\"><strong>Hepcidin the manager</strong></span></h2>\n<p>Hepcidin practices just in time management.   He makes  sure the iron is made available, only when it is needed.  Because hepcidin understands life exists on the interface of too much and too little iron.</p>\n<p style=\"text-align: center;\">When you’re insulin resistant, hepcidin levels are UP. This is not an accident, it is strategic.</p>\n<p><img class=\"aligncenter size-full wp-image-19153\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/low-grade-inflammation.png\" alt=\"low grade inflammation increases hepcidin\" width=\"448\" height=\"226\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/low-grade-inflammation.png 448w, https://betterbodychemistry.com/wp-content/uploads/2019/01/low-grade-inflammation-300x151.png 300w\" sizes=\"(max-width: 448px) 100vw, 448px\" /></p>\n<p style=\"text-align: center;\">But over time, body iron stores increase, unfortunately this stored iron is not accessible.</p>\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-19154\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/body-iron-stores.png\" alt=\"body iron stores \" width=\"371\" height=\"221\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/body-iron-stores.png 371w, https://betterbodychemistry.com/wp-content/uploads/2019/01/body-iron-stores-300x179.png 300w\" sizes=\"(max-width: 371px) 100vw, 371px\" /></p>\n<h3 style=\"text-align: center;\">Clearly, trying to fix the problem by  consuming extra iron, is NOT THE SOLUTION.</h3>\n<h2 style=\"text-align: center;\">You’re NOT SHORT OF IRON !</h2>\n<p style=\"text-align: left;\">The shortage is an “apparent” shortage…..</p>\n<p>In fact, in the long run, it can aggravate the situation. Iron overload is associated with lots of chronic diseases, among them type 2 diabetes, Alzheimer’s and liver failure.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Rein in hepcidin</strong></span></h2>\n<p>You’ve got to lower the  hepcidin.   If you understand the biology, this turns out to be easier than you might think………..</p>\n<p><iframe src=\"https://www.youtube.com/embed/OSdAGbuyRWQ\" width=\"640\" height=\"480\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><span data-mce-type=\"bookmark\" style=\"display: inline-block; width: 0px; overflow: hidden; line-height: 0;\" class=\"mce_SELRES_start\">?</span></iframe></p>\n<h1 style=\"text-align: center;\">REIN IN INSULIN.</h1>\n<p>For tips and strategies, to help you do this, <a href=\"http://www.betterbodychemistry.com/willpower-report/\">download the WILLPOWER REPORT</a>, it’ free.</p>\n\n<div class=\"symple-box yellow none \" style=\"text-align:left; width:100%;\"> <a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214999/\"><strong>Relationship between Serum Levels of Body Iron Parameters and Insulin Resistance and Metabolic Syndrome in Korean Children</strong></a>. Osong Public Health Res Perspect (2014) 5(4) : 204e210. Hye-Ja Lee, Han Byul Jang, Ji Eun Park, Kyung-Hee Park, Jae Heon Kang, Sang Ick Park, Jihyun Song.</p>\n<p><a href=\"https://doi.org/10.3945/an.116.013961/\"><strong>Regulation of the Iron Homeostatic Hormone Hepcidin</strong>.</a> Adv Nutr (2017) 8:126–36. Veena Sangkhae and Elizabeta Nemeth</p>\n<p><a href=\"https://doi.org/10.1080/03007995.2017.1394833/\"><strong>Iron deficiency beyond erythropoiesis: should we be concerned?</strong></a> Current Medical Research and Opinion (2018) 34(1): 81–93. Khaled M. Musallam & Ali T. Taher.</div>\n<h2>Further reading</h2>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p><img class=\"aligncenter size-full wp-image-14720\" src=\"https://betterbodychemistry.com/wp-content/uploads/2015/08/siderocalin-hiding-the-iron-in-the-bladder-tn.png\" alt=\"siderocalin hiding th iron\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2015/08/siderocalin-hiding-the-iron-in-the-bladder-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2015/08/siderocalin-hiding-the-iron-in-the-bladder-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2015/08/siderocalin-hiding-the-iron-in-the-bladder-tn-55x55.png 55w, https://betterbodychemistry.com/wp-content/uploads/2015/08/siderocalin-hiding-the-iron-in-the-bladder-tn-55x55@2x.png 110w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/bacteria/avoid-urinary-tract-infections/\">To avoid UTIs you need to shore up your body’s defences</a></p>\n<p>A urinary tract infection is definitely unpleasant. But, before you reach for the antibiotic, you might want to try something really simple.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-13967\" src=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/adrenaline-kicking-up-a-storm-tn.png\" alt=\"adrenaline kicking up a storm\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2014/09/adrenaline-kicking-up-a-storm-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2014/09/adrenaline-kicking-up-a-storm-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2014/09/adrenaline-kicking-up-a-storm-tn-55x55.png 55w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p> <a href=\"http://www.betterbodychemistry.com/heart-disease/bacteria-dispatch-letter-bomb/\">When you GO POSTAL, your bacteria dispatch a letter bomb</a></p>\n<p>Bacteria need iron to grow, so iron levels are ALWAYS kept low, except during STRESSFUL moments, when iron is made available……. bacteria come out to play</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-last symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-11521\" src=\"https://betterbodychemistry.com/wp-content/uploads/2013/02/iron-causing-the-pancreas-to-rust-tn.png\" alt=\"iron causing the pancreas to rust\" width=\"125\" height=\"125\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/diabetes/iron-pump-diabetes/\">Turning down an iron pump – irons out diabetes</a></p>\n<p>When an iron pump in the pancreas runs full steam for too long, beta cells die and diabetes begins. Turning the pump down, is enough to stop diabetes.</p>\n</div>\n<h2 style=\"text-align: center;\"><span style=\"color: #c33035;\">Want to discover more ways to create BETTER BODY CHEMISTRY ?</span></h2>\n<div class=\'_form_1213\'></div><script type=\'text/javascript\' src=\'https://spoonfulofscience.activehosted.com/f/embed.php?id=1213&5C9179B1E0F96&nostyles=1\'></script>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/ir/hepcidin-insulin-resistance/\">Hepcidin in insulin resistance</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:36:\"http://wellformedweb.org/CommentAPI/\";a:1:{s:10:\"commentRss\";a:1:{i:0;a:5:{s:4:\"data\";s:68:\"https://betterbodychemistry.com/ir/hepcidin-insulin-resistance/feed/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:38:\"http://purl.org/rss/1.0/modules/slash/\";a:1:{s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:1:\"0\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}}}i:7;a:6:{s:4:\"data\";s:69:\"\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n \n \n \n \n \n \";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";s:5:\"child\";a:5:{s:0:\"\";a:7:{s:5:\"title\";a:1:{i:0;a:5:{s:4:\"data\";s:46:\"Diet doesn’t matter if you live outside\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"link\";a:1:{i:0;a:5:{s:4:\"data\";s:58:\"https://betterbodychemistry.com/obesity/diet-live-outside/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:66:\"https://betterbodychemistry.com/obesity/diet-live-outside/#respond\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:7:\"pubDate\";a:1:{i:0;a:5:{s:4:\"data\";s:31:\"Thu, 24 Jan 2019 05:58:21 +0000\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"category\";a:10:{i:0;a:5:{s:4:\"data\";s:7:\"Obesity\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:1;a:5:{s:4:\"data\";s:9:\"circadian\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:2;a:5:{s:4:\"data\";s:7:\"diurnal\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:3;a:5:{s:4:\"data\";s:6:\"inside\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:4;a:5:{s:4:\"data\";s:10:\"laboratory\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:5;a:5:{s:4:\"data\";s:5:\"light\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:6;a:5:{s:4:\"data\";s:9:\"nocturnal\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:7;a:5:{s:4:\"data\";s:7:\"outside\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:8;a:5:{s:4:\"data\";s:8:\"sand rat\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:9;a:5:{s:4:\"data\";s:8:\"sunshine\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"guid\";a:1:{i:0;a:5:{s:4:\"data\";s:40:\"https://betterbodychemistry.com/?p=19088\";s:7:\"attribs\";a:1:{s:0:\"\";a:1:{s:11:\"isPermaLink\";s:5:\"false\";}}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:11:\"description\";a:1:{i:0;a:5:{s:4:\"data\";s:445:\"<p>Despite being “wiredâ€� to be diurnal, many people “actâ€� like they’re nocturnal, the reason for this contrarian behaviour, inside light is NOT the same as outside light. </p>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/obesity/diet-live-outside/\">Diet doesn’t matter if you live outside</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:32:\"http://purl.org/dc/elements/1.1/\";a:1:{s:7:\"creator\";a:1:{i:0;a:5:{s:4:\"data\";s:8:\"Dr Sandy\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:40:\"http://purl.org/rss/1.0/modules/content/\";a:1:{s:7:\"encoded\";a:1:{i:0;a:5:{s:4:\"data\";s:14498:\"<p><iframe src=\"https://www.youtube.com/embed/62_q7SurMQQ\" width=\"640\" height=\"480\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"></iframe></p>\n\n<p>Click to listen to the audio…</p>\n<p><script type=\"text/javascript\" src=\"//spoonfulofscience.audello.com/player/d2hlcmUteW91LWxpdmUtbWF0dGVycy1tb3JlLXRoYW4td2hhdC15b3UtZWF0Lm1wMw==/?container=audello-5NI0TY02BX\" async></script></p>\n<div id=\"audello-5NI0TY02BX\" class=\"audello-player audello-file\" data-role=\"audello-file\" data-audello-id=\"d2hlcmUteW91LWxpdmUtbWF0dGVycy1tb3JlLXRoYW4td2hhdC15b3UtZWF0Lm1wMw==\"></div>\n<h1 style=\"text-align: center;\">Diet doesn’t matter if you live outside</h1>\n<p><img class=\"alignright size-full wp-image-19136\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/sandrat-under-lights.png\" alt=\"fat sand rat living under electric lights\" width=\"402\" height=\"609\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/sandrat-under-lights.png 402w, https://betterbodychemistry.com/wp-content/uploads/2019/01/sandrat-under-lights-198x300.png 198w, https://betterbodychemistry.com/wp-content/uploads/2019/01/sandrat-under-lights-198x300@2x.png 396w\" sizes=\"(max-width: 402px) 100vw, 402px\" />And you’re a sand rat.</p>\n<p>I know, I know…………… you’re not a sand rat, but just like a sand rat, you’re biologically wired to be diurnal i.e.</p>\n<h3 style=\"text-align: center;\">You DO, in the day and SLEEP at night.</h3>\n<p>Now this pattern of behaviour, is NOT what is seen in your typical lab rat. Lab rats come from nocturnal stock i.e.</p>\n<h3 style=\"text-align: center;\">They SLEEP in the day and DO, at night.</h3>\n<p>It’s a subtle difference, but a BIGGIE…………</p>\n<p>Clearly what happens to a sand rat, is likely to be more relevant to you, than what happens to a lab rat.   Humans ARE wired to be diurnal, even if you think you’re a night owl  !</p>\n<h2><span style=\"color: #f21f02;\"><strong>Why aren’t we studying sand rats ?</strong></span></h2>\n<p>Now you might be thinking………….</p>\n<h3 style=\"text-align: center;\"><em>Hello, why aren’t we studying sand rats more ?</em></h3>\n<p>Well the short answer is………….. sand rats, along with other rodents that are diurnal, don’t DO WELL, in labs.  When the little guys get popped in a cage and fed standard rat chow, they get fat, become diabetic and many of them, actually pass to the other side.</p>\n<p style=\"text-align: center;\">As I said………….. they don’t DO WELL !</p>\n<p>But, this doesn’t happen, if they’re kept outside. This is what a group of Israeli researchers recently discovered.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Happy healthy sand rats</strong></span></h2>\n<p>Potter around in hot dry places in North Africa and the Mediterranean, feeding on a low calorie salt bush, by day.</p>\n<p>When they are brought into a lab and fed, salt bush, they don’t seem to suffer, from all the metabolic mayhem. So the take home message for sand rats is</p>\n<h3 style=\"text-align: center;\">Don’t overeat, it makes you FAT and SICK.</h3>\n<p>Which is the same message we humans hear from health gurus…. but for sand rats its WORSE !</p>\n<p>Remember, standard lab rat chow is NOT considered a BAD DIET.  Well the human minders don’t consider is BAD, who knows what the rats think.</p>\n<p>Let’s get back to THIS STUDY……….</p>\n<h2><span style=\"color: #f21f02;\"><strong>Sand rats “pigâ€� out</strong></span></h2>\n<p>In this study, the sand rats where not on “dietâ€�……</p>\n<h3 style=\"text-align: center;\">They sat around in cages, eating  standard rat chow.</h3>\n<p style=\"text-align: center;\">But they remained “perfectlyâ€� healthy.</p>\n<p>The only thing that was different, the sand rats were OUTSIDE, not INSIDE.</p>\n<p><span style=\"color: #f21f02;\"><strong>Inside is the problem ?</strong></span></p>\n<p>So what is the difference between being outside and inside ?</p>\n<p style=\"text-align: center;\">A gazzillion things.</p>\n<h3 style=\"text-align: center;\">Inside there are no bugs, no predators, no weather and “NO LIGHTâ€�.</h3>\n<p>Okay, there is light, but the light is “differentâ€�.</p>\n<h2><span style=\"color: #f21f02;\"><strong>“Differentâ€� light</strong></span></h2>\n<p>In this study, the researchers went to great lengths to ensure that the timing of the light was the same, for the sand rats, inside the lab, as well as outside the lab.</p>\n<p>They did this, by adjusting when the lights went on and off, so as to perfectly match the daylight cycle outdoors. This meant at the start of the study, both groups of sand rats experienced 10 hours and 40 min of day, and by the end of the study, some 9 weeks later, the day length had increased to 12 hours and 39 minutes.</p>\n<h3 style=\"text-align: center;\">So day length was NOT different.</h3>\n<p>But light intensity was…………</p>\n<h2><span style=\"color: #f21f02;\"><strong>Light bulbs are NOT sunshine</strong></span></h2>\n<p>No matter how bright the lights are inside, they don’t compare to the amount of light you experience outside.  <span style=\"text-align: center;\">Even on a cloudy day.</span></p>\n<p><img class=\"aligncenter size-full wp-image-19137\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/sun-and-electric-light-different.png\" alt=\"sunlight versus electric light\" width=\"480\" height=\"270\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/sun-and-electric-light-different.png 480w, https://betterbodychemistry.com/wp-content/uploads/2019/01/sun-and-electric-light-different-300x169.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/01/sun-and-electric-light-different-320x180.png 320w\" sizes=\"(max-width: 480px) 100vw, 480px\" />Now for the sand rats, this is an issue…………</p>\n<p>When they tracked, the animal’s behaviours, they found, inside sand rats lost track of time.</p>\n<h2><span style=\"color: #f21f02;\"><strong>No longer diurnal</strong></span></h2>\n<p>Instead of eating in the day and sleeping at night, they did………</p>\n<h2 style=\"text-align: center;\">WHATEVER.</h2>\n<p>This can be seen here, the yellow shows, what the outside sand rats were up to, while the grey, shows how they behaved inside.  You can see, they became couch potatoes and ate more dinner, in the wee eyes of the night.</p>\n<p><img class=\"aligncenter size-full wp-image-19138\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/sand-rats-graph-1.png\" alt=\"Graph showing the activity of sand rats living outside versus sand rats living in a lab\" width=\"480\" height=\"270\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/sand-rats-graph-1.png 480w, https://betterbodychemistry.com/wp-content/uploads/2019/01/sand-rats-graph-1-300x169.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/01/sand-rats-graph-1-320x180.png 320w\" sizes=\"(max-width: 480px) 100vw, 480px\" /></p>\n<p><em>Interestingly enough, they didn’t actually eat MORE food. The timing of when they ate, was different.</em></p>\n<h2 style=\"text-align: center;\">Basically they became………… NOCTURNAL.</h2>\n<p>And suffered the consequences, becoming FATTER and less glucose tolerant.</p>\n<p><img class=\"aligncenter size-full wp-image-19139\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/sand-rats-graph-2.png\" alt=\"Graph showing sand rat weights and glucose tolerance when living outside versus indoors\" width=\"480\" height=\"270\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/sand-rats-graph-2.png 480w, https://betterbodychemistry.com/wp-content/uploads/2019/01/sand-rats-graph-2-300x169.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/01/sand-rats-graph-2-320x180.png 320w\" sizes=\"(max-width: 480px) 100vw, 480px\" /></p>\n<h2><span style=\"color: #f21f02;\"><strong>“Nocturnalâ€� humans</strong></span></h2>\n<p>Are common.  Despite being “wiredâ€� to be diurnal, many people  “actâ€� like they’re nocturnal.</p>\n<p>Maybe this is not all that surprising………….</p>\n<h2 style=\"text-align: center;\"><strong>Humans are living under “LAB conditionsâ€�.</strong></h2>\n<p><img class=\"aligncenter size-full wp-image-19140\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/the-rat-race.png\" alt=\"human living under lab conditions\" width=\"916\" height=\"511\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/the-rat-race.png 916w, https://betterbodychemistry.com/wp-content/uploads/2019/01/the-rat-race-300x167.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/01/the-rat-race-768x428.png 768w, https://betterbodychemistry.com/wp-content/uploads/2019/01/the-rat-race-320x180.png 320w, https://betterbodychemistry.com/wp-content/uploads/2019/01/the-rat-race-300x167@2x.png 600w, https://betterbodychemistry.com/wp-content/uploads/2019/01/the-rat-race-320x180@2x.png 640w\" sizes=\"(max-width: 916px) 100vw, 916px\" /></p>\n<p>I know we don’t like to think about it this way, but in modern societies,</p>\n<ul>\n<li>food is available ad libitum 24/7 and</li>\n<li>we control our ambient temperature and light exposure.</li>\n</ul>\n<h3 style=\"text-align: center;\">This is what happens in a laboratory.</h3>\n<p style=\"text-align: left;\"><em>And when it come to light exposure , we’ve got it completely back to front. We’re exposed to low levels of light during the day and relatively high levels at night.</em></p>\n<h2><span style=\"color: #f21f02;\"><strong>Lessons from our sand rat cousins</strong></span></h2>\n<p>The plea from these researchers is that more research should be done on diurnal creatures.</p>\n<h2 style=\"text-align: center;\">I AGREE !</h2>\n<p style=\"text-align: left;\">But in the mean time, if you want BETTER BODY CHEMISTRY, you need to be mindful of your diurnal wiring.</p>\n<h3 style=\"text-align: center;\">Make it a goal, to get out of the “labâ€�…………. and live MORE outside.</h3>\n<p style=\"text-align: center;\"><em>You might just find, what you eat, doesn’t matter quite as much !</em></p>\n\n<div class=\"symple-box yellow none \" style=\"text-align:left; width:100%;\"> <a href=\"https://doi.org/10.1177/0748730 /\"><strong>Diurnality, Type 2 Diabetes, and Depressive-Like Behavior. </strong></a> JOURNAL OF BIOLOGICAL RHYTHMS (2019). Carmel Bilu Paul Zimmet, Vicktoria Vishnevskia-Dai, Haim Einat, Galila Agam, Ehud Grossman, and Noga Kronfeld-Schor.</div>\n<h2>Further reading</h2>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-13754\" src=\"https://betterbodychemistry.com/wp-content/uploads/2014/05/fat-cell-stepping-into-the-light-tn.png\" alt=\"fat cell stepping into the light\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2014/05/fat-cell-stepping-into-the-light-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2014/05/fat-cell-stepping-into-the-light-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2014/05/fat-cell-stepping-into-the-light-tn-55x55.png 55w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/obesity/skinny-light-early/\">Want to be skinny – step into the light EARLY</a></p>\n<p>A dose of bright light, before noon, might be just what you need to be lighter on your toes, timing of exposure to light impacts weight</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-13846\" src=\"https://betterbodychemistry.com/wp-content/uploads/2014/08/insulin-setting-the-livers-clock-tn.png\" alt=\"insulin setting liver clock\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2014/08/insulin-setting-the-livers-clock-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2014/08/insulin-setting-the-livers-clock-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2014/08/insulin-setting-the-livers-clock-tn-55x55.png 55w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/obesity/midnight-feasts-bigger-hips/\">Why midnight feasts cause bigger hips</a></p>\n<p>If you eat, when you should be asleep, the enzymes contracted to work the night shift clock in for work, but they don’t do the work, so fat burning ceases.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-last symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-13070\" src=\"https://betterbodychemistry.com/wp-content/uploads/2013/10/line-up-your-schedule-with-your-body-tn.png\" alt=\"collection of organs holding their clocks\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2013/10/line-up-your-schedule-with-your-body-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2013/10/line-up-your-schedule-with-your-body-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2013/10/line-up-your-schedule-with-your-body-tn-55x55.png 55w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/sleep/body-clock-diary/\">It is time to co-ordinate your diary with your body’s schedule</a></p>\n<p>Modern living is CLOCK LIVING, but just like you, Mother Nature is time sensitive. You need to co-ordinate your diary with your body’s schedule.</p>\n</div>\n<h2 style=\"text-align: center;\"><span style=\"color: #c33035;\">Want to discover more ways to create BETTER BODY CHEMISTRY ?</span></h2>\n<div class=\'_form_1213\'></div><script type=\'text/javascript\' src=\'https://spoonfulofscience.activehosted.com/f/embed.php?id=1213&5C9179B1E66B1&nostyles=1\'></script>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/obesity/diet-live-outside/\">Diet doesn’t matter if you live outside</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:36:\"http://wellformedweb.org/CommentAPI/\";a:1:{s:10:\"commentRss\";a:1:{i:0;a:5:{s:4:\"data\";s:63:\"https://betterbodychemistry.com/obesity/diet-live-outside/feed/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:38:\"http://purl.org/rss/1.0/modules/slash/\";a:1:{s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:1:\"0\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}}}i:8;a:6:{s:4:\"data\";s:75:\"\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n \n \n \n \n \n \";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";s:5:\"child\";a:5:{s:0:\"\";a:7:{s:5:\"title\";a:1:{i:0;a:5:{s:4:\"data\";s:50:\"How food makes us HOT and HOT makes us STOP eating\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"link\";a:1:{i:0;a:5:{s:4:\"data\";s:56:\"https://betterbodychemistry.com/obesity/hot-stop-eating/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:64:\"https://betterbodychemistry.com/obesity/hot-stop-eating/#respond\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:7:\"pubDate\";a:1:{i:0;a:5:{s:4:\"data\";s:31:\"Thu, 10 Jan 2019 05:59:18 +0000\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"category\";a:12:{i:0;a:5:{s:4:\"data\";s:7:\"Obesity\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:1;a:5:{s:4:\"data\";s:8:\"appetite\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:2;a:5:{s:4:\"data\";s:3:\"BAT\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:3;a:5:{s:4:\"data\";s:15:\"brown fat cells\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:4;a:5:{s:4:\"data\";s:4:\"cold\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:5;a:5:{s:4:\"data\";s:3:\"hot\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:6;a:5:{s:4:\"data\";s:7:\"satiety\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:7;a:5:{s:4:\"data\";s:8:\"secretin\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:8;a:5:{s:4:\"data\";s:15:\"small intestine\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:9;a:5:{s:4:\"data\";s:7:\"stomach\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:10;a:5:{s:4:\"data\";s:11:\"temperature\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:11;a:5:{s:4:\"data\";s:13:\"thermogenesis\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"guid\";a:1:{i:0;a:5:{s:4:\"data\";s:40:\"https://betterbodychemistry.com/?p=19019\";s:7:\"attribs\";a:1:{s:0:\"\";a:1:{s:11:\"isPermaLink\";s:5:\"false\";}}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:11:\"description\";a:1:{i:0;a:5:{s:4:\"data\";s:395:\"<p>Meal associated thermogenesis, is one of the ways, our body flips the off switch on eating – discover how to use this biology to your advantage</p>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/obesity/hot-stop-eating/\">How food makes us HOT and HOT makes us STOP eating</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:32:\"http://purl.org/dc/elements/1.1/\";a:1:{s:7:\"creator\";a:1:{i:0;a:5:{s:4:\"data\";s:8:\"Dr Sandy\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:40:\"http://purl.org/rss/1.0/modules/content/\";a:1:{s:7:\"encoded\";a:1:{i:0;a:5:{s:4:\"data\";s:14213:\"<p><iframe src=\"https://www.youtube.com/embed/axTaqxiQMKA\" width=\"640\" height=\"480\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"></iframe></p>\n\n<p>Click to listen to the audio…<br />\n<script type=\"text/javascript\" src=\"//spoonfulofscience.audello.com/player/aG93LXRvLWVhdC1sZXNzLWFuZC1mZWVsLWZ1bGxlci5tcDM=/?container=audello-D81VZVK19K\" async></script></p>\n<div id=\"audello-D81VZVK19K\" class=\"audello-player audello-file\" data-role=\"audello-file\" data-audello-id=\"aG93LXRvLWVhdC1sZXNzLWFuZC1mZWVsLWZ1bGxlci5tcDM=\"></div>\n<h1 style=\"text-align: center;\">How to eat less and feel fuller</h1>\n<p><img class=\"alignright size-full wp-image-19118\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/meal-associated-thermogenesis-fb.png\" alt=\"man experiencing meal associated thermogenesis\" width=\"401\" height=\"673\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/meal-associated-thermogenesis-fb.png 401w, https://betterbodychemistry.com/wp-content/uploads/2019/01/meal-associated-thermogenesis-fb-179x300.png 179w, https://betterbodychemistry.com/wp-content/uploads/2019/01/meal-associated-thermogenesis-fb-179x300@2x.png 358w\" sizes=\"(max-width: 401px) 100vw, 401px\" />Eating is a warming experience.</p>\n<p>Seriously.</p>\n<p>This is one of the reason’s we eat more in winter. The presence of food in the belly, makes us feel warm and toasty.</p>\n<p>The term for this is meal associated thermogenesis.</p>\n<h2><span style=\"color: #f21f02;\"><strong>I like it warm NOT hot</strong></span></h2>\n<p>Now, feeling warm and toasty is NICE. But, there is a fine line between warm and toasty AND HOT.</p>\n<h3 style=\"text-align: center;\">HOT is not particularly attractive.</h3>\n<h3 style=\"text-align: center;\">So, avoiding HOT, following a meal, is prudent.</h3>\n<p>And it’s one of the reasons, our body, flips the off switch on eating.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Flipping the switch</strong></span></h2>\n<p>Now the existence of the switch is NOT news.</p>\n<p style=\"text-align: center;\">But how it works is.</p>\n<p>A team of researchers from Germany, have managed to piece it all together.</p>\n<p style=\"text-align: center;\">It’s complicated.</p>\n<p style=\"text-align: center;\">But, it’s potentially exploitable.</p>\n<h2><span style=\"color: #f21f02;\"><strong>That acid MUST be neutralized</strong></span></h2>\n<p>To get digestion STARTED…………… acid is required, so food takes a dip in the acid vat of the stomach.  Big bits of protein are chopped and diced, into smaller peptides, which slip out the stomach, into the small intestine, for further processing.</p>\n<p style=\"text-align: center;\">But the small bits of food are embedded in an acid sludge.</p>\n<p>Ouch ! The acid MUST be neutralized………….</p>\n<p>Cells in the upper small intestine, known as S cells, reach out to the pancreas for help.</p>\n<p><img class=\"aligncenter size-full wp-image-19119\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/S-cells-calling-for-secretin-to-neutralize-acid.png\" alt=\"S cells signalling for secretin\" width=\"684\" height=\"425\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/S-cells-calling-for-secretin-to-neutralize-acid.png 684w, https://betterbodychemistry.com/wp-content/uploads/2019/01/S-cells-calling-for-secretin-to-neutralize-acid-300x186.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/01/S-cells-calling-for-secretin-to-neutralize-acid-300x186@2x.png 600w\" sizes=\"(max-width: 684px) 100vw, 684px\" /></p>\n<h2><span style=\"color: #f21f02;\"><strong>S is for SECRETIN</strong></span></h2>\n<p>The pancreas obliges, neutralizing the acid, by squirting in, bicarbonate containing pancreatic juice.</p>\n<h3 style=\"text-align: center;\">Processing and absorption proceeds.</h3>\n<p>But the pancreas is NOT the only organ in the body, that hears the small intestine “screechingâ€�.</p>\n<h2><span style=\"color: #f21f02;\"><strong>The sound travels </strong></span></h2>\n<p>Despite being, a million miles away for the digestive tract…………. brown fat cells, hear the “screechingâ€�.</p>\n<h3 style=\"text-align: center;\">The sound chills them to the bone, sparking a flurry of activity.</h3>\n<p>Here is a FDG-PET-CT scan showing what happens to BAT cells, when someone is injected with secretin.</p>\n<div id=\"attachment_19120\" style=\"width: 680px\" class=\"wp-caption aligncenter\"><img class=\"size-full wp-image-19120\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/secretin-activating-BAT-cells.png\" alt=\"FDG-PET-CT of BAT cells infused with secretin\" width=\"670\" height=\"367\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/secretin-activating-BAT-cells.png 670w, https://betterbodychemistry.com/wp-content/uploads/2019/01/secretin-activating-BAT-cells-300x164.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/01/secretin-activating-BAT-cells-300x164@2x.png 600w\" sizes=\"(max-width: 670px) 100vw, 670px\" /><p class=\"wp-caption-text\">FDG-PET-CT scan showing glucose uptake following secretin infusion. Copyright 2018 Elsevier Inc</p></div>\n<h3 style=\"text-align: center;\">The BAT cells begin spewing out fire and brimstone.</h3>\n<p>This is HOT WORK !</p>\n<h2><span style=\"color: #f21f02;\"><strong>Neurons get hot and bothered</strong></span></h2>\n<p>Now among the neurons in the body, that are exquisitely sensitive to the heat, are a set of neurons, deep inside the ARC nucleus.</p>\n<h3 style=\"text-align: center;\">These guys control your appetite.</h3>\n<h2 style=\"text-align: center;\">The hot causes them to shut down feeding.</h2>\n<p>To avoid a case of heat stroke………….it’s the</p>\n<p><img class=\"aligncenter size-full wp-image-19122\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/gut-secretin-bat-brain-axis.png\" alt=\"the gut-secretin-bat-brain axis\" width=\"671\" height=\"276\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/gut-secretin-bat-brain-axis.png 671w, https://betterbodychemistry.com/wp-content/uploads/2019/01/gut-secretin-bat-brain-axis-300x123.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/01/gut-secretin-bat-brain-axis-300x123@2x.png 600w\" sizes=\"(max-width: 671px) 100vw, 671px\" /></p>\n<p style=\"text-align: center;\">This happens in mice and men.</p>\n<p>So how can this be exploited ?</p>\n<h2><span style=\"color: #f21f02;\"><strong>Turn up the heat<img class=\"alignright size-full wp-image-19123\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/thirsty-rat.png\" alt=\"rat drinking and excreting lots of water\" width=\"334\" height=\"397\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/thirsty-rat.png 334w, https://betterbodychemistry.com/wp-content/uploads/2019/01/thirsty-rat-252x300.png 252w\" sizes=\"(max-width: 334px) 100vw, 334px\" /></strong></span></h2>\n<p>Well one idea is to increase secretin.</p>\n<p style=\"text-align: center;\">The researchers tried it.</p>\n<p>They injected mice with recombinant secretin, this could stop them eating, but the effect on weight was small and it came at a price…………</p>\n<p>So don’t expect a secretin mimetic drug pill, to be on the market in the foreseeable future.</p>\n<p>But this doesn’t mean, you can’t turn up the heat.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Eat for more secretin</strong></span></h2>\n<p>Your digestive tract notices what’s in the bites you take………….</p>\n<p> </p>\n<p>It has to be, getting a fat “digestedâ€� requires a completely different set of tools, to a protein or carb.</p>\n<h3 style=\"text-align: center;\">As a rule, more acid is needed to digest protein.</h3>\n<h2 style=\"text-align: center;\">More acid, needs MORE secretin.</h2>\n<p><em>So try to obey the rules of thirds, at every meal i.e. eat a little protein, a little fat and a little carb, to optimize gut hormone signalling.  And avoid using antacids meds on a routine basis !</em></p>\n<h2><span style=\"color: #f21f02;\"><strong>Bring on the BAT </strong></span></h2>\n<p>Now BAT is one of those things you can be blessed with lots of, or be “deficientâ€�.</p>\n<p>Your BAT levels are probably less about genetics and more about your living conditions. In short, if you want to be endowed with lots of BAT cells, you need to FREEZE YOUR TUSH off, on a regular basis.</p>\n<p>Seriously……….</p>\n<h3 style=\"text-align: center;\">BAT is your built in body heater.</h3>\n<p><img class=\"aligncenter wp-image-19121 size-full\" src=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/BAT-cells-warming-person-up.png\" alt=\"lady being warmed by BAT cells\" width=\"674\" height=\"397\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2019/01/BAT-cells-warming-person-up.png 674w, https://betterbodychemistry.com/wp-content/uploads/2019/01/BAT-cells-warming-person-up-300x177.png 300w, https://betterbodychemistry.com/wp-content/uploads/2019/01/BAT-cells-warming-person-up-300x177@2x.png 600w\" sizes=\"(max-width: 674px) 100vw, 674px\" /></p>\n<p>If there’s not much call for it, you don’t make it. And, as a rule, people with weight issues, typically are somewhat “deficientâ€�.</p>\n<h2><span style=\"color: #f21f02;\"><strong>More BAT more burn</strong></span></h2>\n<p>Since BAT cells, burn lots of calories – they’re pretty useful, in and of themselves. But this research suggests, that they are more than a catabolic heater, they also control appetite.</p>\n<p style=\"text-align: center;\"><em>And if you have a tendency to overeat, this can be most helpful.</em></p>\n<p>More BAT, would mean a bigger burn, after eating. The bigger burn, would bring warmer temperatures to the appetite control centre, resulting in an earlier shut down of eating.</p>\n<h3 style=\"text-align: center;\">Less calories in = less calories to process !</h3>\n<p>A weight watching WIN, with the help of BIOLOGY, not PSYCHOLOGY. <a href=\"http://www.betterbodychemistry.com/willpower-report/\">Click here</a> to download the free “Willpower Report” to discover more biological tools to tame your sugar gremlin</p>\n\n<div class=\"symple-box yellow none \" style=\"text-align:left; width:100%;\"> <a href=\"https://doi.org/10.1016/j.cell.2018.10.016/\"><strong>Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation</strong></a>. Cell  (2018) 175 : 1–14. Yongguo Li, Katharina Schnabl, Sarah-Madeleine Gabler, Monja Willershauser, Josefine Reber, Angelos Karlas, Sanna Laurila, Minna Lahesmaa, Mueez u Din, Andrea Bast-Habersbrunner, Kirsi A. Virtanen, Tobias Fromme, Florian Bolze,Libbey S. O’Farrell, Jorge Alsina-Fernandez, Tamer Coskun,  Vasilis Ntziachristos, Pirjo Nuutila, and Martin Klingenspor.  </div>\n<h2>Further reading</h2>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-15873\" src=\"https://betterbodychemistry.com/wp-content/uploads/2016/05/BAT-sugar-burn-tn.png\" alt=\"BAT cell burning sugar\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2016/05/BAT-sugar-burn-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2016/05/BAT-sugar-burn-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2016/05/BAT-sugar-burn-tn-55x55.png 55w, https://betterbodychemistry.com/wp-content/uploads/2016/05/BAT-sugar-burn-tn-55x55@2x.png 110w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/diabetes/burn-sugar-at-dawn/\">You should burn sugar when you get out of bed – do you ?</a></p>\n<p>Every morning, just before dawn, brown fat cells burn sugar, to warm you up. They’ll do it, even if you’re insulin resistant, as long as they’re there.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-13398\" src=\"https://betterbodychemistry.com/wp-content/uploads/2014/01/a-fat-cell-transplant-tn.png\" alt=\"a fat cell transplant\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2014/01/a-fat-cell-transplant-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2014/01/a-fat-cell-transplant-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2014/01/a-fat-cell-transplant-tn-55x55.png 55w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/obesity/christmas-fat-transplant/\">All I want for Christmas is a fat transplant</a></p>\n<p>Mice who receive a FAT transplant become OBESITY RESISTANT – this means, the little critters can eat what they like and never get fat. I want that….</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-last symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-9343\" src=\"https://betterbodychemistry.com/wp-content/uploads/2012/06/cold-thermogenesis-tn.png\" alt=\"cold thermogenesis\" width=\"126\" height=\"125\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/obesity/cold-shoulder-fat-meltdown/\">Being given the cold shoulder causes a fat meltdown</a></p>\n<p>Cold sweats and cold baths both burn calories, but cold baths trump cold sweats – so if you’re up to it, a cold bath is a cool way to burn those extra calories.</p>\n</div>\n<h2 style=\"text-align: center;\"><span style=\"color: #c33035;\">Want to discover more ways to create BETTER BODY CHEMISTRY ?</span></h2>\n<div class=\'_form_1213\'></div><script type=\'text/javascript\' src=\'https://spoonfulofscience.activehosted.com/f/embed.php?id=1213&5C9179B1EBC59&nostyles=1\'></script>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/obesity/hot-stop-eating/\">How food makes us HOT and HOT makes us STOP eating</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:36:\"http://wellformedweb.org/CommentAPI/\";a:1:{s:10:\"commentRss\";a:1:{i:0;a:5:{s:4:\"data\";s:61:\"https://betterbodychemistry.com/obesity/hot-stop-eating/feed/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:38:\"http://purl.org/rss/1.0/modules/slash/\";a:1:{s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:1:\"0\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}}}i:9;a:6:{s:4:\"data\";s:75:\"\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n \n \n \n \n \n \";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";s:5:\"child\";a:5:{s:0:\"\";a:7:{s:5:\"title\";a:1:{i:0;a:5:{s:4:\"data\";s:49:\"Baroreceptor sensitivity in the insulin resistant\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"link\";a:1:{i:0;a:5:{s:4:\"data\";s:79:\"https://betterbodychemistry.com/ir/baroreceptor-sensitivity-insulin-resistance/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:87:\"https://betterbodychemistry.com/ir/baroreceptor-sensitivity-insulin-resistance/#respond\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:7:\"pubDate\";a:1:{i:0;a:5:{s:4:\"data\";s:31:\"Thu, 20 Dec 2018 08:08:54 +0000\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:8:\"category\";a:12:{i:0;a:5:{s:4:\"data\";s:2:\"IR\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:1;a:5:{s:4:\"data\";s:3:\"ANS\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:2;a:5:{s:4:\"data\";s:24:\"autonomic nervous system\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:3;a:5:{s:4:\"data\";s:14:\"blood pressure\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:4;a:5:{s:4:\"data\";s:8:\"exercise\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:5;a:5:{s:4:\"data\";s:7:\"gravity\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:6;a:5:{s:4:\"data\";s:12:\"hypertension\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:7;a:5:{s:4:\"data\";s:7:\"insulin\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:8;a:5:{s:4:\"data\";s:17:\"insulin resistant\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:9;a:5:{s:4:\"data\";s:18:\"metabolic syndrome\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:10;a:5:{s:4:\"data\";s:15:\"parasympathetic\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}i:11;a:5:{s:4:\"data\";s:11:\"sympathetic\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:4:\"guid\";a:1:{i:0;a:5:{s:4:\"data\";s:40:\"https://betterbodychemistry.com/?p=19047\";s:7:\"attribs\";a:1:{s:0:\"\";a:1:{s:11:\"isPermaLink\";s:5:\"false\";}}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:11:\"description\";a:1:{i:0;a:5:{s:4:\"data\";s:433:\"<p>We look at how agile your baroreceptors are, or should I say, aren’t and why this matters, in this week\'s episode of the UPS & DOWNS of insulin resistance</p>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/ir/baroreceptor-sensitivity-insulin-resistance/\">Baroreceptor sensitivity in the insulin resistant</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:32:\"http://purl.org/dc/elements/1.1/\";a:1:{s:7:\"creator\";a:1:{i:0;a:5:{s:4:\"data\";s:8:\"Dr Sandy\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:40:\"http://purl.org/rss/1.0/modules/content/\";a:1:{s:7:\"encoded\";a:1:{i:0;a:5:{s:4:\"data\";s:13593:\"<p><iframe src=\"https://www.youtube.com/embed/f4dYNL2Xeds\" width=\"640\" height=\"480\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"></iframe></p>\n\n<p>Click to listen to the audio…</p>\n<p><script type=\"text/javascript\" src=\"//spoonfulofscience.audello.com/player/YmFyb3JlY2VwdG9yc2F2ZS5tcDM=/?container=audello-YL0GDCXRU8\" async></script></p>\n<div id=\"audello-YL0GDCXRU8\" class=\"audello-player audello-file\" data-role=\"audello-file\" data-audello-id=\"YmFyb3JlY2VwdG9yc2F2ZS5tcDM=\"></div>\n<p><a href=\"https://prezi.com/p/ruipndp5p8zr/\">Click here</a> to view the prezi.</p>\n<p>When you’re insulin resistant, that is, you’ve got  metabolic syndrome, pretty much every chemical in the body is NOT QUITE RIGHT. Some are up. Some are down. Few are actually at physiologically NORMAL levels.</p>\n<p>Traditionally the focus is on the big guns.</p>\n<ul>\n<li>Sugar</li>\n<li>Insulin</li>\n<li>And cholesterol</li>\n</ul>\n<p>In this series, we  take a look at some of the other players.</p>\n<p>Who they are, what they’re up to and how they’re part of the state of insulin resistance.</p>\n<p>This week, we’re not actually looking at a chemical <em>per se</em>, instead we take a look at the behaviour of tiny little pressure receptors, called baroreceptors, which are embedded in the blood vessels, that leave the heart.</p>\n<h2 style=\"text-align: center;\"><strong> Baroreceptor sensitivity in the insulin resistant</strong></h2>\n<p>Baroreceptor sensitivity is reduced, which in a nut shell, means, your heart is not able to roll with the punches, quite as well as it should.</p>\n<p>What should happen….</p>\n<h2><span style=\"color: #f21f02;\">Heart adjustments</span></h2>\n<p><img class=\"aligncenter size-full wp-image-19049\" src=\"https://betterbodychemistry.com/wp-content/uploads/2018/12/heart-adjustments.png\" alt=\"heart adjustments when you change posture\" width=\"522\" height=\"246\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2018/12/heart-adjustments.png 522w, https://betterbodychemistry.com/wp-content/uploads/2018/12/heart-adjustments-300x141.png 300w\" sizes=\"(max-width: 522px) 100vw, 522px\" /></p>\n<p>If your situation changes, let’s say for example, you have to stand up quickly, what you need / want your heart to do will change.</p>\n<p style=\"text-align: center;\">Lying down is a walk in the park – because there is NO GRAVITY.</p>\n<h3 style=\"text-align: center;\">Standing up…….. NOT SO MUCH.</h3>\n<h2><span style=\"color: #f21f02;\"><strong>Whoozey </strong></span></h2>\n<p>The blood goes rushing to your toes and if your heart is caught napping, you should feel a little whoozey, in the moment.</p>\n<h1 style=\"text-align: center;\">But you don’t.</h1>\n<p>Thanks to your baroreceptor sensitivity…….</p>\n<h2><span style=\"color: #f21f02;\"><strong>The baroreceptors</strong></span></h2>\n<p>Little pressure receptors, keep tabs on the blood pressure. The drop is quickly noticed……………. a message is sent up to the brain stem, hinting at a looming crisis.  The brain stem responds, instructing the blood vessels to narrow and the heart to beat a little faster……………….</p>\n<p><img class=\"aligncenter size-full wp-image-19050\" src=\"https://betterbodychemistry.com/wp-content/uploads/2018/12/baroreceptor-reflex.png\" alt=\"baroreceptor reflex\" width=\"516\" height=\"304\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2018/12/baroreceptor-reflex.png 516w, https://betterbodychemistry.com/wp-content/uploads/2018/12/baroreceptor-reflex-300x177.png 300w\" sizes=\"(max-width: 516px) 100vw, 516px\" /></p>\n<h3 style=\"text-align: center;\">And, the problem is solved.</h3>\n<p>Of course, if your next move is to RELAX – then the reverse happens.</p>\n<p>The little pressure sensor notices that the pressure is a tad on the high side. It shoots a message to the brain stem, reporting on the situation. The brain stem, makes the necessary adjustments.</p>\n<p style=\"text-align: center;\">Blood vessels widen, the heart rate slows.</p>\n<h3 style=\"text-align: center;\">It’s so quick, you never notice.</h3>\n<p>But, how quick it is………………ends up being a reflection of your metabolic status.</p>\n<h2><span style=\"color: #f21f02;\">Slow on the uptake</span></h2>\n<p>If you are insulin resistant – the speed at which you make the adjustment is slower. Now, this is not really a BIG deal, in the moment.</p>\n<h3 style=\"text-align: center;\">YOU MAKE THE ADJUSTMENT.</h3>\n<p>But, it is a sign that the system is OFF balance….</p>\n<h2><span style=\"color: #f21f02;\">Off balance</span></h2>\n<p>Specifically the balance between the sympathetic and parasympathetic system is compromised.  Since these nerves, collectively known as the autonomic nervous system, run your body, behind the scenes, think autoMATIC, it has implications for your health across the board.</p>\n<p><a href=\"c nervous system\"><img class=\"aligncenter size-full wp-image-19051\" src=\"https://betterbodychemistry.com/wp-content/uploads/2018/12/autonomic-system-balance.png\" alt=\"scheme showing autonomi\" width=\"676\" height=\"350\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2018/12/autonomic-system-balance.png 676w, https://betterbodychemistry.com/wp-content/uploads/2018/12/autonomic-system-balance-300x155.png 300w, https://betterbodychemistry.com/wp-content/uploads/2018/12/autonomic-system-balance-300x155@2x.png 600w\" sizes=\"(max-width: 676px) 100vw, 676px\" /></a></p>\n<p>So, reduced basoreceptor sensitivity is NOT the ideal……</p>\n<h2><span style=\"color: #f21f02;\">A compromised response</span></h2>\n<p>It means, your body’s ability to respond to situations, is compromised.</p>\n<h3 style=\"text-align: center;\">The question is why ?  Is it the cause or the consequence.</h3>\n<p style=\"text-align: left;\">The short answer. We don’t really know.  I suspect, it’s probably a little of both, changes in sympatho-vagal balance are since, very early on in metabolic syndrome.</p>\n<p style=\"text-align: center;\">High insulin, morning, noon and night, is probably a BIG part of the problem.</p>\n<p style=\"text-align: center;\"><em>Watch this video to understand learn more. </em></p>\n<p><iframe src=\"https://www.youtube.com/embed/U_rZA3_SBlA\" width=\"640\" height=\"480\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><span data-mce-type=\"bookmark\" style=\"display: inline-block; width: 0px; overflow: hidden; line-height: 0;\" class=\"mce_SELRES_start\">?</span></iframe></p>\n<p>So, if you want to improve your baroreceptor sensitivity…….</p>\n<h1 style=\"text-align: center;\">REIN IN INSULIN.</h1>\n<p>For tips and strategies, to help you do this, <a href=\"http://www.betterbodychemistry.com/willpower-report/\">download the WILLPOWER REPORT</a>, it’ free.</p>\n<h2><span style=\"color: #f21f02;\"><strong>Control sympatho-vagal balance</strong></span></h2>\n<p>The sympatho-vagal balance is more than just a major controller.</p>\n<h3 style=\"text-align: center;\">IT CAN BE CONTROLLED !</h3>\n<p><img class=\"aligncenter size-full wp-image-19052\" src=\"https://betterbodychemistry.com/wp-content/uploads/2018/12/control-of-the-sympatho-vagal-balance.png\" alt=\"man controlling sympatho-vagal balance\" width=\"518\" height=\"299\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2018/12/control-of-the-sympatho-vagal-balance.png 518w, https://betterbodychemistry.com/wp-content/uploads/2018/12/control-of-the-sympatho-vagal-balance-300x173.png 300w\" sizes=\"(max-width: 518px) 100vw, 518px\" /></p>\n<p>Now the lifestyle habit, that will bring a lot of bang for the buck, is physical activity…..</p>\n<h3 style=\"text-align: center;\">It’s a case of PRACTICE MAKES PERFECT.</h3>\n<p style=\"text-align: center;\">People who move more, need the system to be tuned in, to avoid DISASTERS.</p>\n<p>But, when it comes to lifestyle and behaviours, physical activity is the tip of the iceberg, literally, everything you do…………. tips the balance, one way or the other.</p>\n<h2 style=\"text-align: center;\"><span style=\"color: #f21f02;\">It’s a lever YOU CAN PULL.</span></h2>\n<p><img class=\"aligncenter size-full wp-image-19053\" src=\"https://betterbodychemistry.com/wp-content/uploads/2018/12/factors-influencing-sympatho-vagal-balance.png\" alt=\"factors that influence sypatho-vagal balance\" width=\"603\" height=\"335\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2018/12/factors-influencing-sympatho-vagal-balance.png 603w, https://betterbodychemistry.com/wp-content/uploads/2018/12/factors-influencing-sympatho-vagal-balance-300x167.png 300w, https://betterbodychemistry.com/wp-content/uploads/2018/12/factors-influencing-sympatho-vagal-balance-300x167@2x.png 600w\" sizes=\"(max-width: 603px) 100vw, 603px\" /></p>\n<p>It’s a matter of figuring out, what works for you and DOING it. I’ll be looking at these in an upcoming series.</p>\n<p><em>NOTE : It’s not like diet and exercise, which are often quite challenging. Many of the factors that move the needle, are “nice” to do. If you’re NOT DOING THEM, it’s often because you don’t appreciate their value. </em></p>\n\n<div class=\"symple-box yellow none \" style=\"text-align:left; width:100%;\"> <strong><a href=\"https://doi.org/10.5603/CJ.2013.0130\">Baroreceptor sensitivity and diabetes mellitus.</a></strong> Cardiology Journal (2013) 20 (5) :  453–463.  Olumide Olatubosun Rowaiye, Ewa Anita Jankowska, Beata Ponikowska.</p>\n<p><a href=\"https://doi.org/10.4103/ijmr.IJMR_1751_16/\"><strong>Contribution of insulin resistance to decreased baroreceptor sensitivity & cardiometabolic risks in pre-obesity & obesity.</strong></a> Indian J Med Res (2018) 148 : 151-158.  Jagadeeswaran Indumathy, Gopal Krushna Pal, Pravati Pal, Palakkad Hariharan Ananthanarayanan, Subash Chandra Parija, Jayaraman Balachander & Tarun Kumar Dutta.</p>\n<p><a href=\"https://doi.org/10.1016/bs.pbr.2018.09.002/\"><strong>Enhancing cardiac vagal activity: Factors of interest for sport psychology</strong></a>. Prog Brain Res (2018) 240 : 71-92. Sylvain Laborde, Emma Mosley, Lea Ueberholz.</div>\n<h2>Further reading</h2>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-12632\" src=\"https://betterbodychemistry.com/wp-content/uploads/2013/08/happy-heart-giving-tn.png\" alt=\"heart with a monocle\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2013/08/happy-heart-giving-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2013/08/happy-heart-giving-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2013/08/happy-heart-giving-tn-55x55.png 55w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/heart-disease/volunteering-lowers-inflammation/\">Volunteering creates a little slack in tight blood vessels</a></p>\n<p>Volunteering might be just the thing you need to loosen up those “tightâ€� blood vessels. Not metaphorically speaking, literally.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-first symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-13864\" src=\"https://betterbodychemistry.com/wp-content/uploads/2014/08/happy-hearts-singing-in-the-choir-tn.png\" alt=\"happy hearts singing in the choir\" width=\"125\" height=\"125\" srcset=\"https://betterbodychemistry.com/wp-content/uploads/2014/08/happy-hearts-singing-in-the-choir-tn.png 125w, https://betterbodychemistry.com/wp-content/uploads/2014/08/happy-hearts-singing-in-the-choir-tn-83x83.png 83w, https://betterbodychemistry.com/wp-content/uploads/2014/08/happy-hearts-singing-in-the-choir-tn-55x55.png 55w\" sizes=\"(max-width: 125px) 100vw, 125px\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/heart-disease/singing-hearts-beating-harmoniously/\">Singing in the choir gets hearts beating more harmoniously</a></p>\n<p>So get tralla lala laling. Singing together means breathing together. And breathing is good for the nerves, which is good for the heart.</p>\n</div>\n<div class=\"symple-column symple-one-third symple-column-last symple-all\">\n<p style=\"text-align: center;\"><img class=\"aligncenter size-full wp-image-4983\" src=\"https://betterbodychemistry.com/wp-content/uploads/2011/07/happy-heart-sad-heart-tn.png\" alt=\"happy heart sad heart tn\" width=\"125\" height=\"125\" /></p>\n<p><a href=\"http://www.betterbodychemistry.com/thinking/laughing-good-medicine-soul-helps-heart/\">Laughing is not just good medicine for the soul it helps the heart too</a></p>\n<p>If you put on the running shoes and jiggled up and down, you would get the blood flowing but a good laugh does the same thing without the sweat and tears.</p>\n</div>\n<h2 style=\"text-align: center;\"><span style=\"color: #c33035;\">Want to discover more ways to create BETTER BODY CHEMISTRY ?</span></h2>\n<div class=\'_form_1213\'></div><script type=\'text/javascript\' src=\'https://spoonfulofscience.activehosted.com/f/embed.php?id=1213&5C9179B1F0FB3&nostyles=1\'></script>\n<p>The post <a rel=\"nofollow\" href=\"https://betterbodychemistry.com/ir/baroreceptor-sensitivity-insulin-resistance/\">Baroreceptor sensitivity in the insulin resistant</a> appeared first on <a rel=\"nofollow\" href=\"https://betterbodychemistry.com\">BBC</a>.</p>\n\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:36:\"http://wellformedweb.org/CommentAPI/\";a:1:{s:10:\"commentRss\";a:1:{i:0;a:5:{s:4:\"data\";s:84:\"https://betterbodychemistry.com/ir/baroreceptor-sensitivity-insulin-resistance/feed/\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:38:\"http://purl.org/rss/1.0/modules/slash/\";a:1:{s:8:\"comments\";a:1:{i:0;a:5:{s:4:\"data\";s:1:\"0\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}}}}}s:27:\"http://www.w3.org/2005/Atom\";a:1:{s:4:\"link\";a:1:{i:0;a:5:{s:4:\"data\";s:0:\"\";s:7:\"attribs\";a:1:{s:0:\"\";a:3:{s:4:\"href\";s:37:\"https://betterbodychemistry.com/feed/\";s:3:\"rel\";s:4:\"self\";s:4:\"type\";s:19:\"application/rss+xml\";}}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}s:44:\"http://purl.org/rss/1.0/modules/syndication/\";a:2:{s:12:\"updatePeriod\";a:1:{i:0;a:5:{s:4:\"data\";s:6:\"hourly\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}s:15:\"updateFrequency\";a:1:{i:0;a:5:{s:4:\"data\";s:1:\"1\";s:7:\"attribs\";a:0:{}s:8:\"xml_base\";s:0:\"\";s:17:\"xml_base_explicit\";b:0;s:8:\"xml_lang\";s:0:\"\";}}}}}}}}}}}}s:4:\"type\";i:128;s:7:\"headers\";a:18:{s:6:\"server\";s:5:\"nginx\";s:4:\"date\";s:29:\"Tue, 19 Mar 2019 23:24:05 GMT\";s:12:\"content-type\";s:34:\"application/rss+xml; charset=UTF-8\";s:10:\"connection\";s:5:\"close\";s:4:\"vary\";s:15:\"Accept-Encoding\";s:12:\"x-powered-by\";s:10:\"PHP/5.6.40\";s:7:\"expires\";s:29:\"Thu, 19 Nov 1981 08:52:00 GMT\";s:13:\"cache-control\";s:62:\"no-store, no-cache, must-revalidate, post-check=0, pre-check=0\";s:6:\"pragma\";s:8:\"no-cache\";s:12:\"x-robots-tag\";s:15:\"noindex, follow\";s:4:\"link\";s:68:\"<https://betterbodychemistry.com/wp-json/>; rel=\"https://api.w.org/\"\";s:10:\"set-cookie\";s:44:\"PHPSESSID=uiiim96dcfs28p2rulnaqs9jb1; path=/\";s:13:\"last-modified\";s:29:\"Thu, 14 Mar 2019 07:00:48 GMT\";s:4:\"etag\";s:34:\"\"26dec9edd9517dce4ff99ece8cf8ee39\"\";s:16:\"x-xss-protection\";s:13:\"1; mode=block\";s:22:\"x-content-type-options\";s:7:\"nosniff\";s:20:\"x-nginx-cache-status\";s:3:\"HIT\";s:19:\"x-server-powered-by\";s:10:\"Texo Nginx\";}s:5:\"build\";s:14:\"20140103145553\";}', 'no') ON DUPLICATE KEY UPDATE `option_name` = VALUES(`option_name`), `option_value` = VALUES(`option_value`), `autoload` = VALUES(`autoload`)
Better body chemistry
- Gallstones are NOT a cholesterol problem
- The calorie label on that packet of nuts is wrong
- Endotoxin in insulin resistance
- The chemistry behind angry moments
- When your iron deficiency is NOT an iron deficiency
- When to take an aspirin to lower your cardiovascular risk
- Hepcidin in insulin resistance
- Diet doesn’t matter if you live outside
- How food makes us HOT and HOT makes us STOP eating
- Baroreceptor sensitivity in the insulin resistant